Head of Oncology Clinical Development

Employer
GSK
Location
Collegeville, Pennsylvania; Zug, Switzerland; Waltham, Massachusetts
Salary
Competitive
Closing date
Oct 2, 2022

View more

Discipline
Life Sciences, Oncology
Job Type
Manager
Organization Type
Pharma
Are you a visionary Oncology Development leadership executive looking to lead an ambitious team with deep expertise in development cutting edge cancer treatments? If so, this position may be of interest.

GSK R&D

We're combining the power of genetic and genomic insights into what causes disease, with the speed and scale of artificial intelligence and machine learning (AI/ML) to make better predictions about who a treatment might work for, and why. We believe this powerful combination of data and technology holds the key to fundamentally transforming medical discovery for the better, improving R&D success rates and shaping how even the most challenging diseases, like neurological conditions and cancer, can be both prevented and treated.

In 2021 we delivered four major product approvals: Cabenuva for HIV, Jemperli for endometrial cancer, Xevudy for COVID-19 and Apretude , our new long-acting medicine for HIV prevention.

Find out more:

Our approach to R&D .

GSK Oncology R&D

Our Oncology R&D organization is building a diverse portfolio of Oncology medicines, focused on maximizing patient survival through transformation medicines. We aim to deliver first-to-market and first-in-class solutions that have the potential to address some of the biggest challenges in oncology.

Our organization covers the entire research and development spectrum from discovery to clinical development and regulatory compliance. We partner with other R&D functions, including Commercial and Medical to build our pipeline, manage trials, and progress from development to commercialization. We also pursue and manage critical business development opportunities, collaborations and acquisitions to advance our mission. ​​

GSK continues to be committed to the discovery and development of new oncology therapies with the life-changing potential of helping patients with cancer, specifically in four areas of cancer research:

•Immuno-Oncology - Focused on an innovative pipeline of immune modulators designed to leverage a patient's immune system to recognize and eradicate solid and liquid tumors.
• Cell/Gene Therapy - Engineering next generation cell therapies for treatment of advanced malignancies.
•Tumor Cell Targeting - Target tumor-specific alterations to introduce selective anti-cancer activity.
Synthetic Lethality - Optimizing the use of PARP-inhibitors and delivering a Repertoire of Synthetic Lethal Medicines.

For more information:


JOB DESCRIPTION:

The Head of Clinical Development reports to the SVP Global Head of Oncology Development and is the senior clinical development expert within Oncology Development with oversight for the development strategies across all programs of the Oncology asset portfolio. In this role the successful candidate will lead the definition of development strategies and co-define disease area strategy across OneOncology (R&D, Medical Affairs and Commercial). The Head of clinical development has direct line function responsibility for all clinical personnel including medical directors and clinical scientists. They work in a matrix role to support Early Development Teams (EDTs) for preparing programs for entry into clinical development and Medicine Development Teams (MDTs) for driving clinical strategy for late-stage assets.

Further, the Head of clinical Development chairs the Protocol Review Forum (PRF) ensuring highest level quality for all TA clinical protocols. They are a member of the Portfolio Review Committee (PRC) overseeing asset progression across the portfolio and participates in governance committee reviews for R&D assets. The position reports to the TA Head of Oncology.

The Head of Clinical Development provides clinical development expertise, strategic leadership, Oncology disease area expertise, and Prescriber Insight for Oncology Clinical Development. They play a pivotal role in setting up disease area strategies, and in ensuring the quality and robustness of the medicine vision, clinical development plans and the integrated evidence plans for the Oncology Clinical Development assets in order to support the development, approval, commercialization and patient access to differentiated medicines with proven value and with a positive return on investment for GSK. The role will also contribute to Medical Governance at the organizational level.

KEY RESPOSIBILITIES:
  • T he Head of Oncology Clinical Development provides significant input on clinical plans, medical governance at a TA level and ensure appropriate and adequate clinical resourcing. In partnership with Franchise, they define disease area strategies and priorities, ensure patient focus and robust evidence package to support successful commercialization and patient access to GSK medicines. They are also accountable for the ethical conduct of studies in the Oncology TA.
  • They are the single point of accountability for medical governance at the Oncology Clinical Development level. The role will also ensure adequate clinical oversight of clinical research initiatives, and provide a global and objective viewpoint of safety and efficacy by cultivating and sustaining a culture of openness and transparency with patient well-being as the key driver in decision-making
  • This individual will lead a team of empowered and motivated clinical development staff, driving a compelling vision and aligning the team to achieve success in developing assets in Oncology.
  • This position will also contain extensive matrix management and, where relevant, the management of external vendors.
  • The Head of Oncology Clinical Development is responsible for championing clinical excellence at the TA level through talent identification, recruitment, retention and development, including succession planning.
  • The role is responsible for overall pipeline and portfolio delivery in Oncology, working extensively with Regulatory Affairs, Medical Affairs, Commercial, Health Outcomes and other relevant departments.
  • The Head of Oncology Clinical Development will also be responsible for exploring opportunities for simplification, ensuring that the TA is as effective and as efficient as possible

*LI-GSK

# LI-Hybrid

#LI-Onsite

Candidate Profile

Professional experience/minimum qualifications
  • Medical Doctor with Board Qualification (or equivalent) in Medical Oncology or related Oncology Specialty
  • Extensive line and matrix management
  • Considerable pharmaceutical industry experience is required
  • Understands the entirety of R&D across the development/commercial life cycle to allow impact across all functions: discovery, late stage development, regulatory, manufacturing and commercial
  • Track record of success working in highly complex, matrixed, global, and multi-disciplinary organization with high accountability, minimal authority, and multiple lines of reporting
  • Proven ability to strategize, prioritize, and manage multiple projects simultaneously to ensure quality, timely, on-target and within budget accomplishment of tasks
  • Attention to detail while discriminating between critical and non-critical activities, and to follow established processes while identifying areas for process improvement
  • Excellent planning, time management and organizational skills
  • Exemplary communication and presentation skills, high- level negotiation skills and the ability to resolve conflict in a constructive manner


Preferred Qualifications:
  • MD/PhD preferred
  • Relevant experience in early phase drug development is an advantage
  • Highly developed ethics and integrity, with demonstrated ethical medical decision-making skills.


Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years.

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued and included. Where they can keep growing and look after their wellbeing.So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

At GSK, the health and safety of our employees are of paramount importance. As a science-led healthcare company on a mission to get ahead of disease together, we believe that supporting vaccination against COVID-19 is the single best thing we can do in the US to ensure the health and safety of our employees, complementary workers, workplaces, customers, consumers, communities, and the patients we serve.

GSK has made the decision to require all US employees to be fully vaccinated against COVID-19, where allowed by state or local law and where vaccine supply is readily available. The only exceptions to this requirement are employees who are approved for an accommodation for religious, medical or disability-related reasons.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.



    GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years.

    Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy. We're committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.

    If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

    GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

    At GSK, the health and safety of our employees are of paramount importance. As a science-led healthcare company on a mission to get ahead of disease together, we believe that supporting vaccination against COVID-19 is the single best thing we can do in the US to ensure the health and safety of our employees, complementary workers, workplaces, customers, consumers, communities, and the patients we serve.

    GSK has made the decision to require all US employees to be fully vaccinated against COVID-19, where allowed by state or local law and where vaccine supply is readily available. The only exceptions to this requirement are employees who are approved for an accommodation for religious, medical or disability-related reasons.

    Important notice to Employment businesses/ Agencies

    GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

    Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.

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