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Senior Associate Scientist, Tumor Biology--Translational Sciences

La Jolla, California
Closing date
Sep 25, 2022

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Life Sciences, Biology, Physical Sciences, Chemistry
Position Type
Full Time
Job Type
Staff Scientist
Organization Type
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You will join a dynamic ream of scientists in our Translational Sciences group, playing a leading role in the characterization of models of cancer and evaluating new drug candidates. You will participate in pre-clinical drug discovery and development projects with a focus on targeted therapeutics, epigenetics and the tumor microenvironment. You will characterize and develop small molecules in close collaboration with partner lines as an integral member of drug discovery teams. You will evaluate anti-tumor effects of single agents or in combination with other modalities, employing and developing new cutting-edge in vivo cancer models and provide technical and scientific expertise in in vivo pharmacology to enable target identification, validation, prioritization, and efficient drug discovery of small molecules in Tumor Biology.

  • Assist and/or conduct in vivo studies to evaluate and establish efficacy, PK/PD relationship, combination strategy, biomarker identification and analysis.
  • Interpretation, presentation and documentation of experiments.
  • Presentation of results within a multidisciplinary team environment.
  • Regularly read scientific papers and implement learnings in the study designs or project strategies.

  • BS degree with a minimum 3 years related laboratory work experience in academia or industry experience or MS degree in Cancer Biology, Immunology or similar discipline
  • Experience following novel scientific or technological developments, and implementing them in the laboratory.
  • Hands on In vivo skills (IV, PO dosing), blood/tissue collections
  • Experience with in vivo models
  • Excellent written and oral communication and presentation skills.
  • Experience integrating biological concepts into experimental design

  • Ex vivo skills such as Western blot is a plus
  • Experience with GraphPad Prism and/or Studylog is a plus

  • Lifting, sitting, standing, walking, bending, ability to perform mathematical calculations
  • Must be able to wear specialized protective clothing and PPE (lab coat, safety shoes/glasses/etc).


  • Must be willing and able to work after hours as needed to ensure study integrity

Relocation support available

Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development

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