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Manager, Biomarker Statistician

Cambridge, Massachusetts
Closing date
Sep 23, 2022

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Physical Sciences, Statistics
Position Type
Full Time
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Manager, Biomarker Statistician wanted by Pfizer in Cambridge, MA.

Analyze clinical biomarker data including high dimensional data types such as lipidomics, proteomics, and transcriptomics data. Collaborate with Precision Medicine (PM) scientists and clinicians in the design, analysis and reporting of multi-dimensional biomarker data in early clinical trials. Define and evolve best practices across the group and partner with Research Units, Business Technology (BT) and partner line bioinformatics experts to align approaches, develop best practices, and assess and develop new technology.Ensure high-quality data analysis is incorporated into clinical exploratory-research programs in an objective fashion, facilitated by contribution of Exploratory Analysis Plans and summary of results, in partnership with other team members. Collaborate with research unit scientists in the design, analysis and reporting of genetics and 'omics analyses to enable decisions on target selection and prioritization. Partner closely with RUs, Clinical Teams, Statistics, BT and PM functions to identify, pilot and incorporate new bioinformatics tools to support clinical trials.

Requires: Ph.D. degree or foreign equivalent in statistics, computational biology, bioinformatics, or closely related field, plus 2 years of experience in the pharmaceutical industry in job offered or as Senior Research Statistician. Also requires 1 year of experience with/using the following (which may have been gained concurrently): working with high dimensional exploratory biomarker platforms (e.g. transcriptomics); applying statistical methods to the prospective design and analysis of scientific and/or clinical problems; SAS, R to perform big data analysis and data visualization; applying statistical analytical methods to genetics and omics data analysis; using early phase clinical study design principles, including power and sample size calculations; writing clinical biomarker SAPs; performing simulation, bootstrapping and permutation testing in a multidimensional modeling setting; analyzing linear mixed models; developing, influencing and championing biomarker analysis strategies with scientific team audiences and management.

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Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

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