Postdoctoral Fellow - Diabetes Complications and Metabolism

City of Hope
Duarte, California
Closing date
Oct 12, 2022

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Life Sciences
Position Type
Full Time
Organization Type

Job Details

About City of Hope

City of Hope, an innovative biomedical research,treatment and educational institution with over 6,000 employees, is dedicatedto the prevention and cure of cancer, type 1 diabetes, type 2 diabetes andother life-threatening diseases and guided by a compassionate, patient-centeredphilosophy.

City of Hope has one of the most influential type 1 and type 2 diabetesresearch programs in the world. Our scientists' work has revolutionized theunderstanding and treatment of the disease and continues today with excitingdevelopments in cell transplantation, gene regulation, immune tolerance andgaining systemic understanding of diabetes as a complex, multifaceted disease.

To learn more about our exciting research and accomplishments inthe field of Diabetes, please visit

Position Summary

A Postdoctoral Fellow position is immediately availablein the laboratory of Dr. Ke Ma, Associate Professor, at the Diabetes and MetabolismResearch Institute within Beckman Research Institute of City of Hope, CA. TheMa lab applies state-of-the-art circadian biology, molecular and cellularbiology approaches to diabetes and obesity research, with a goal to unravelcircadian etiologies underlying the current epidemics of metabolic diseases fortargeted therapeutic interventions. We have a unique research program indeciphering the mechanistic underpinnings of circadian clock control inmetabolic tissue development, growth and functional capacity, specifically inskeletal muscle and adipose tissue.

We are seeking a highly motivated postdoctoralfellow with strong enthusiasm for metabolic disease or stem cell research to studymolecular signaling mechanisms underlying circadian clock function in skeletalmuscle and adipose tissue. Candidates with strong training in cell biology,molecular biology and biochemical techniques are preferred, and priorexperience with animal models is a plus. Utilizing biochemical and molecularbiology approaches combined with genetic animal models, specific researchdirections in the lab include: 1) genetic and epigenetic signaling networksmediating circadian clock nutrient-sensing function in adipose tissue andskeletal muscle; 2) circadian clock regulation of skeletal muscle growth and metabolism;and 3) novel signaling mechanisms in core circadian clock regulation.

Thecandidate should be self-motivated, with a proven track record of publicationsand strong interest to pursue metabolic disease research. Expertise in biochemistry,cell biology and animal physiology are preferred. Technical skills in metabolic,epigenetics and stem cell research are a plus.

Basic education, experience and skills required for consideration:
  • PhD in Molecular, Cellular or Developmental Biology.
  • Proficiency with biochemical techniques, molecular biology skills and cell culture systems.
  • Experience with in vivo animal model research preferred.
  • Experience with epigenetics research and bioinformatics analysis a plus.
  • Highly motivated with strong interest in metabolic disease research.
  • Strong work ethic and ability to work effectively in a team.

Additional Information:
  • For more information on Dr. Ke Ma please visit, here
  • For a list of lab publications please visit, here
  • To apply, please provide your current CV, a brief research statement describing your background, experiences and career goals, and a list of three references
  • To protect the health of patients and staff and to comply with new State of California mandates, City of Hope staff are required to show proof of full vaccination by September 30, 2021. Compliance is a condition of employment.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.



City of Hope, an innovative biomedical research, treatment and educational institution with over 5,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research.  City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation’s 20 leading cancer centers that develops and institutes standards of care for cancer treatment.

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