Postdoctoral Fellow

Employer
University of Texas MD Anderson Cancer Center
Location
Houston, Texas
Salary
Competitive
Closing date
Oct 3, 2022

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Discipline
Health Sciences
Organization Type
Healthcare/Hospital
We are seeking an enthusiastic Postdoctoral Researcher to study how macrophages can resolve nerve injury and pain through enhanced efferocytosis. Investigations will be performed using transgenic mice, preclinical models of neuropathic pain, and in vitro studies. Experience in working with rodents and a background in pain or immunology is preferred. The position is funded by an NIH grant and is available immediately. We highly value innovation, learning, hard work, creativity, and an interactive, respectful and fun atmosphere. The post-doctoral fellow will work under the direct supervision of the principal investigator on this NIH-funded project.

If you are interested in helping to understand the molecular and cellular mechanisms of pain and developing novel interventions to help improve the quality of life for people suffering from chronic pain in an internationally-renowned, well-funded group of scientists using a highly integrated and interdisciplinary approach in the number one cancer center in the USA, we are the perfect environment for you!

ESSENTIAL FUNCTIONS

Research Activity:
Macrophage isolations and culture
Live cell imaging
Luciferase assays and immunoassays
Nerve injury surgery
Intrathecal drug treatments in vivo
Behavioral assays of pain in rodents
Collect and process ex vivo biological samples including nerve, brain, spinal cord
Immunohistochemistry and microscopy studies on cells and nervous system tissues
Western blotting and qPCR
Flow cytometry
Present results in departmental and national meetings
Prepare and write manuscripts for publication.

Interpersonal Skills, Communication, Learning Skills
Strong written and oral communication skills
Communication with faculty and staff within and outside the laboratory.
Ability to work with others in a highly collaborative manner.
Good problem-solving abilities.

Other
Responsible for monitoring laboratory equipment and implementing safety procedures.
Strong interest in basic and translational research
Supervision of 1-2 research assistants

LEARNING OBJECTIVES
Applicants will gain experience in preclinical research methods, with an emphasis on understanding cellular and behavioral consequences of neuropathic pain. They will become proficient with advanced biochemical techniques employed in preclinical neuroimmunology research and develop advanced skills in the organization, presentation, and analysis of data.

ELIGIBILITY REQUIREMENTS
We are looking for a post-doctoral researcher with a strong background in Immunology to study the molecular and cellular consequences of peripheral nerve injury in mouse models. Experience with Flow Cytometry, cell culture, confocal microscopy, and rodent behavior would be of great value for the research.

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