Postdoctoral Fellow

Employer
University of Texas MD Anderson Cancer Center
Location
Houston, Texas
Salary
Competitive
Closing date
Oct 8, 2022

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Discipline
Health Sciences
Organization Type
Healthcare/Hospital
The University of Texas MD Anderson Cancer Center invites applications for postdoctoral fellowships in experimental cancer biology, CRISPR, and functional genetics/epigenetics starting immediately. Using state-of-the-art gene-editing and functional genomics/proteomics techniques, we seek to identify genetic and epigenetic biomarkers for human cancer precision medicine, synthetic lethal and resistance mechanisms underlying disease development, and signal transduction at the systems level.

The postdoctoral research will be performed in a highly interdisciplinary and collaborative environment with world-class experts, advanced technologies, and facilities, providing unique and ideal career development opportunities for postdocs. Successful candidates will be supervised by Dr. Nidhi Sahni, a faculty member and recognized leader in cancer genetics and systems biology at MD Anderson Cancer Center. Dr. Sahni has received numerous prestigious awards and strong funding support, including AACR NextGen Star, Sloan Scholar Award, CPRIT Scholar Award, NIH Outstanding Investigator Award (MIRA), DoD grant, Pinnacle Research Award, and Rising STARs Award, among others.

Recent representative publications include Cancer Cell (2020), 37: 371-86; Cell (2015), 161: 647-60; Nature Rev Genet (2017), 18: 395-410; Cancer Cell (2018), 33: 450-462; Cell (2015), 161: 661-73; Cell (2017), 168: 856-66; Nature Commun. (2018), 9: 1317. For more information, please visit https://faculty.mdanderson.org/profiles/nidhi_sahni.html

LEARNING OBJECTIVES
The trainee will learn how to execute and design high throughput screens using CRISPR-Cas9, reporter assays, single-cell technologies, and Perturb Seq assys combing CRISPR with sc-RNA/sc-ATAC. The trainee will participate in collaborative projects and present findings at a prestigious national/international conference.

ELIGIBILITY REQUIREMENTS
Applicants should have a recent Ph.D. degree (or equivalent) in molecular biology, cancer biology, genetics/epigenetics, immunology, or relevant fields. We are interested in passionate and self-motivated candidates who ask fundamentally important questions and are bold in taking innovative approaches. Candidates should have previous expertise with tissue culture. Experience with high-throughput biology, CRISPR screens, and next-generation sequencing is a plus.

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