Research Asst II-Cardiology Research

Employer
University of Texas MD Anderson Cancer Center
Location
Houston, Texas
Salary
Competitive
Closing date
Oct 12, 2022

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Discipline
Health Sciences
Organization Type
Healthcare/Hospital
Mission Statement

The mission of The University of Texas M. D. Anderson Cancer Center is to eliminate cancer in Texas, the nation, and the world through outstanding programs that integrate patient care, research and prevention, and through education for undergraduate and graduate students, trainees, professionals, employees and the public.

Summary

Function :

The primary purpose of the Research Assistant II position is to provide technical skills and coordination in carrying out various research projects as assigned in a laboratory studying cardiovascular function and dysfunction at the molecular, cellular, and physiological levels. Coordinates and conducts laboratory experiments in cell culture, molecular biology, and histological experiments. This position will help to train new lab members, including students in experimental technique and will contribute to animal colony maintenance and experimentation.

Scope :

Impacts laboratory research activities.

KEY FUNCTIONS:
  1. Laboratory Research Projects and Experiments:

Assists in handling laboratory animals (mice) and colony maintenance including genotyping, weaning, recording, and pairing. Will participate in harvesting tissues for histological analysis, inject various drugs and AAV virus, changing the special diets, and some animal surgical assistance. After analysis, this data will be used to produce grant applications and publication.
  1. Animal Colony Maintenance and Data Generation:

Assists in collection of data by performing molecular biology experiments, including isolation of protein, DNA and RNA for gel electrophoresis and RT-PCR; immuno-precipitation and ChIP assays; reporter gene assays (luciferase). After analysis, this data will be used to produce grant applications and publications. Isolate, characterize, and culture primary endothelial cells and bone marrow macrophages from mouse

  1. Laboratory Equipment and Maintenance:
  • Assists with general lab duties, including ordering and organization of supplies and reagents.
  • Prepare stock solutions and media, and properly dispose of all hazardous waste.
  • Monitors inventory of chemicals, equipment and general supplies. May train, educate and oversee compliance of new lab workers in proper research techniques and health/safety and animal regulations.
  • As needed, instruct laboratory personnel in appropriate use of equipment and in learning new techniques.

MARGINAL FUNCTIONS:
  1. General Laboratory Operations:
  • Maintains laboratory notebooks and records in accordance with GLPs; Prepare and characterize standards.
  • Write and maintain protocols in accordance with GLPs.
  • May be responsible for shipment of related lab materials. Shipment activities would involve:
  • Must be able to assemble samples, reagents, dry or wet ice, data and packaging materials.
  • Draft a cover letter, accurately and legibly fill out shipping labels
  • Carry package to receiving area on ground floor prior to carrier pickup.
  • Keep accurate and legible logs of outgoing and incoming packages.
  • For incoming packages: ascertain contents, store at appropriate location, file information sheets and notify principal investigator.
  • Update pertinent inventory logs.


Core COMPETENCIES:
  • IC - Analytical Thinking:
    • Gather relevant information systematically;
    • Break down problems into simple components; and
    • Make sound decisions.
  • IC-Oral Communication:
    • Express ideas clearly and concisely in groups and one-to-one conversations;
    • Create an environment with open channels of communication.
  • IC-Written Communication:
    • Convey information clearly and concisely through both formal and informal documents;
    • Adapt writing style to fit the audience.
  • IC - Build Relationships:
    • Initiate, develop, and manage relationships and networks; and
    • Show sincere interest in others and their concerns.
  • IC - Innovative Thinking:
    • Approach problems with curiosity and open-mindedness; and
    • Offer new ideas, solutions and/or options.


TECHNICAL COMPETENCIES:
  • IC-Technical/Functional Expertise:
    • Demonstrate technical proficiency required to do the job;
    • Possess up-to-date knowledge in the profession;
    • Provide technical expertise to others.
  • TC-Equipment Usage & Safety Preparedness -
    • Approach problems with curiosity and open-mindedness; and
    • Offer new ideas, solutions and/or options
    • Employee maintains expectations for safety preparedness, including but not limited to: Orientation to new equipment, Employee Education Event, CPR training, fire drills

Working Conditions

Laboratory environment. This position requires:

Working in Office Environment

____X_ No

______ Yes

Working in Patient Care Unit (e.g. Nursing unit; outpatient clinic)

____X_ No

______ Yes

Exposure to human/animal blood, body fluids, or tissues

______ No

___X__ Yes

Exposure to harmful chemicals

______ No

___X___ Yes

Exposure to radiation

______ No

___X___ Yes

Exposure to animals

______ No

___X___ Yes

Physical Demands

Indicate the time required to do each of the following physical demands:

Time Spent

Never

0%

Occasionally

1-33%

Frequently

34-66%

Continuously

67-100%

Standing

Walking

Sitting

Reaching

Lifting/Carrying

Up to 10 lbs

10lbs to 50 lbs

More than 50 lbs

Pushing/Pulling

Up to 10 lbs

10lbs to 50 lbs

More than 50 lbs

Use computer/keyboard

Working conditions are acceptable but may involve exposure to occasional hazardous equipment and materials. Alertness and careful attention are required to avoid injury to self or others. May require extended periods of standing at a counter. Tasks may involve frequent walking or standing for up to six hours a day. Must be able to work at instrument (standing) for 3-4 hours without a break. Work may involve frequently unscheduled tasks, which must be of very high quality, could be highly repetitive, and may involve unscheduled overtime. May require occasional bending/stooping, reaching, physically handling, walking, or visually inspecting and lifting up to 20 pounds. Also involves problem solving, reasoning, independent decision-making, analyzing, planning and communicating orally and in writing. Use the computer via the keyboard to prepare reports and other documents. Work with infectious agents, toxic chemicals and radioisotopes. Works with personal computers using standard software, i.e., word processing, Excel, database and graphics programs.

ACCURACY:

Precision in preparing materials and recording data is mandatory. Must clearly, accurately, and effectively communicate in English, both face-to-face and over the telephone is required. Must be able to communicate results to and understand instructions from the supervisor. A willingness to cooperate and maintain open communication with other staff, students, research postdoctoral fellows and visitors is essential.

EDUCATION: Bachelor's degree with major course works in one of the basic sciences.

EXPERIENCE: One year experience in scientific or experimental research work. No experience required with preferred degree.

It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html

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