Research Associate

Summary

The overall goal of our research program is to delineate novel pathways that link hepatic metabolism and disease. Specifically, Wilson's disease patients and animal models (such as Atp7b-/- mice) develop severe liver dysfunction and spontaneous hepatic nodule formation. We have several ongoing projects for this area: copper-mediated changes in nuclear receptor function, metabolism, liver regeneration/nodule formation, and autophagy.

Job Duties

• Independently maintain mouse colonies for experimentation.
• Perform research experiments, such as, chromatin immunoprecipitation (ChIP) and ChIP-Seq assays, RNA-Seq assays, Western blotting, and tissue culture.
• Document results and prepare them for presentation.
• Evaluate, analyze, and submit data to the PI.
• Prepare figures for publications, conferences, and grants.
• Help train junior staff and graduate students.
• Conduct literature searches and summarize information for the PI.
• Maintain lab equipment and inventory lists.
• Prepare buffers and reagents for laboratory operations.
• Genotyping and mouse colony management, Western blotting, PCR, real-time PCR, ChIP assays, CRISPR/Cas9 techniques.

Minimum Qualifications

• Master's degree in Basic Science or a related field. Experience in lieu of degree will not be accepted.
• Three years of relevant experience typically as a Research Assistant, Research Technician or Postdoctoral Fellow/Associate.

Preferred Qualifications

• Master's of Science Degree in Biochemistry, Molecular and Cellular Biology, or related fields.
• Must have positive attitude and eagerness to learn new laboratory techniques.
• Should have excellent communication skills and work well with others.
• Knowledge of software programs including R and/or python are preferred but not required.

Baylor College of Medicine requires employees to be fully vaccinated -subject to approved exemptions-against vaccine-preventable diseases including, but not limited to, COVID-19 and influenza.

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.

12880

CA; SN