Senior Research Scientist - Lung Cancer & Spatial Transcriptomics

University of Texas MD Anderson Cancer Center
Houston, Texas
Closing date
Oct 3, 2022

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Health Sciences
Organization Type

The Sr. Research Scientist will help a vibrant laboratory focused on lung cancer development with various experiments. The Sr. Research Scientist will assist in processing human airway and lung tissue samples for bulk and single-cell sequencing analyses. The Sr. Research Scientist will also aid in spatial transcriptomics of normal and cancer tissues. The Sr. Research Scientist will help processing fresh human and murine tissue samples for producing single-cell RNA and TCR/BCR libraries. The Sr. Research Scientist will also assist in performing validation by immunohistochemistry and other imaging techniques.


Technical Functions

Function in an independent manner, and have the ability to design research experiments.
Discusses goals of each project with supervisor; with the help of supervisor, develops a step-by-step written procedure outlining the specific actions required to conduct the experiment before proceeding
Ability to work on several research projects concurrently in an independent manner
Compile research data and submit results to for inclusion in publications, grants or protocols.

Laboratory Operation

The Sr. Research Scientist will be responsible for the following laboratory operations:
Processing fresh and frozen human airway and lung tissue samples for bulk and single-cell sequencing analyses.

Processing fresh normal and cancer tissues for generation of libraries for spatial transcriptomics as well as single-cell RNA and TCR/BCR sequencing.

Perform validation of targets by immunohistochemistry, flow cytometry, and imaging techniques.

Provide technical and coordination expertise in carrying out various research projects, coordinates procedures, and performs technical laboratory duties in accordance with general and/or specific plans.

Collaboration and Presentation

Interacts and participates in collaborative studies inside and outside MD Anderson.
Trains other research personnel and students on established assays, and use of laboratory equipment
Presents research data at internal and external meetings and conferences
Prepare final reports in the format requested for the data generated by suggested due date
Willingness to learn and to help others in the implementation of new techniques

Data Maintenance

Enter and maintain data from research activities in notebook/computer databases as appropriate.
Performs and documents all required quality control/quality assurance.
Maintains accurate, detailed records and experimental data and protocols
Prepares graphs, slides and tables via photography, computer, or manually.
Collaborates or assists supervisor and senior research staff with preparation of reports and grant requests.
Acquires and maintains proficiency in computer functions.
Able to work with database, graphing and word processing computer programs such as Microsoft Excel, Power Point, Word and Prism
Must be able to fully communicate results and understand instructions from principal investigator and colleagues.

Other duties as assigned

Ph.D. in one of the natural sciences or related field or Medical degree. Three years of experience in experimental or scientific work. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law.

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