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Sr. Scientist, Genomic Immunology (Cambridge, MA)

Cambridge, Massachusetts
Closing date
Aug 23, 2022

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GlaxoSmithKline (GSK) is committed to developing medicines for global health challenges including respiratory, immuno-inflammation, oncology and infectious diseases. We know that finding cures means not just finding new drugs but finding new ways to discover drugs.

The Immunology Research Unit identifies and develops novel therapeutic targets for patients with unmet medical need, through leveraging strong genetic datasets, building drug hypotheses from output of functional genomic CRISPR editing screens and performing hands-on experimentation using a wide range of molecular and cellular techniques suitable for drug target identification and validation. Our Genomic Immunologygroup strives to explore that rich data landscape to derive crucial insight, and to integrate directly with our groundbreaking experimental science. This approach maximizes the probability of delivering successful clinical candidates, and ultimately helping people to do more, feel better and live longer.

The Senior Scientist position will reside in the Genomic Immunology Group within the Immunology Department and will be based in Cambridge, MA. It requires a highly motivated and skilled candidate to assist target identification and validation and to take part in the development of novel therapeutics for the treatment of immune disorders with high unmet medical need. This individual will work independently and/or in partnership with cross-functional project dynamic teams in a multidisciplinary matrixed environment to investigate the biology of novel immune targets using functional molecular genomic tools, to evaluate the effects of newly developed drug lead candidates on immune cell functions and to make significant and high-impact contributions in multiple GSK drug discovery programs.

  • Design and perform molecular and cellular assays suitable for drug target identification and validation.
  • Generate, analyze, interpret, present experimental results at various meetings to partners/collaborators and collaboratively plan experimental paths forward
  • Support project teams in collaboration with scientists from multiple functional areas
  • Generate study reports and maintain a detailed record of experiments in electronic lab notebooks in accordance with company policy.
  • Share in responsibilities to support general lab functions

Why you?

Basic Qualifications:
  • Master's Degree in Biology or related field required.

Preferred Qualifications:
  • Master's Degree or Bachelor's Degree with strong knowledge and research experience in the field of immunology and auto-immune diseases, such as such as inflammatory bowel disease, asthma, COPD, or atopic dermatitis etc…
  • Technical expertise in CRISPR, siRNA, multi-color flow cytometry, or mouse inflammatory disease models
  • Strong verbal, written communication skills as well as interpersonal skills
  • Knowledgeable, highly motivated, creative, and collaborative
  • Learning agility and drive to continuously improve and develop
  • Previous drug discovery experience in a biopharmaceutical setting

Why GSK?

At GSK, we have already delivered unprecedented change over the past four years, improving R&D, becoming a leader inConsumer Health, strengthening our leadership, and transforming our commercial execution. Now, we're making the biggestchanges we've made to our business in over 20 years.We're on track to separate and create two new companies in 2022:New GSK with a leading portfolio of vaccines and specialty medicines as well as R&D based on immune system and geneticsscience; and a new world-leading consumer healthcare company of loved and trusted brands.​

With new ambition comes new purpose. For New GSK, this is to unite science, talent and technology to get ahead of diseasetogether - all with the clear ambition of delivering human health impact; stronger and more sustainable shareholder returns; andas a new GSK where outstanding people thrive.​

Getting ahead means preventing disease as well as treating it. How we do all this is through our people and our culture. A culturethat isambitious for patients- so we deliver what matters better and faster;accountable for impact- with clear ownership ofgoals and support to succeed; andwhere we do the right thing. So, if you're ready to improve the lives of billions, join us at thisexciting moment in our journey. Join our challenge to get Ahead Together.​


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