We are building a state-of-the-art
end to end Biopharm capability which delivers efficient discovery
of antibody molecules that are selected and engineered for rapid development so that, together with our therapy area partners, we discover, develop and manufacture
novel portfolio of exciting medicines
to benefit patients around the world.
If you aim to be part of a global cutting edge drug development and discovery organization
and are motivated to contribute towards bringing lifesaving drugs to patients
, join us!
Click to know more about GSK Biopharm. #GSKBiopharm_Development
GlaxoSmithKline (GSK) is a world leading research-based pharmaceutical company that combines both individual talent and technical resources to create a platform for the delivery of strong growth in a rapidly changing healthcare market. Our mission is to improve the quality of human life by enabling people to do more, feel better and live longer.
Biopharm Process Development is a highly experienced Chemistry, Manufacturing and Controls ( CMC ) organization accountable for delivering robust, cost effective and competitive product s and manufacturing process es spanning the full life-cycle of asset development from Discovery through commercialization. These activities are delivered through state-of-the art internal facilities as well as strategic external partners. Collectively, the team is accountable for CMC activities encompassing cell line development, cell culture/ microbial fermentation, purification development, and drug product / device development. We also pioneer innovative technologies to improve robustness, reduce cost of goods, and improve the patient experience.
Within Biopharm Process Development, the Microbial and Cell Culture Development department is responsible for the development of cell culture process es for the manufacture of GSK's Biopharm assets. The Department is also responsible for the scale-up and tech transfer of the process es to manufacturing facilities all over the world. Our aim is to integrate innovative expression and process platforms, automation and advanced data analytics into the upstream process development workflow. An opportunity has arisen for a process development scientist with ability to advance the perfusion platform and handle large sets of complex data . He/she will have the opportunity to develop new methods and build capability in automated workflows and data handling.
In this role, you will be a member of a highly skilled team of scientists and engineers responsible for development and optimization of cell culture process es. The team will have access to the latest technology in small-scale as well as large scale bioreactors and analytical instruments. Although predominantly lab -based, the role also involves important aspects of verbal and written communication and requires good organisation skills as well as a broad scientific knowledge of cellular metabolism and physiology. You will be working in a matrix team and therefore the role will suit a scientist with good interpersonal skills, ability to solve complex problems, is self-motivated and has an open mindset.
Key responsibilities include:
Why you?Basic Qualifications:
- Process development of perfusion-based cell culture process es and transfer to c GMP facilities.
- Execution of small-scale bioreactor studies for development and optimization of perfusion process es, evaluation for facility fit and small-scale model qualification.
- Interacting with colleagues in key partner groups: scientists/engineers involved in scale-up and tech transfer, downstream process development and analytical method development scientists, data scientists and statisticians.
We are looking for professionals with these required skills to achieve our goals:
- Bachelor's or Master's degree in Bio process /Biochemical/Chemical Engineering or related Biological Science
- Experience working in a biological lab oratory and familiarity with general lab oratory procedures.
If you have the following characteristics, it would be a plus:
Why GSK? Uniting science, talent, and technology to get ahead of disease together
- Demonstrated broad knowledge base in routine cell culture and sterile technique
- Excellent interpersonal and communication skills
- Ability to adapt quickly to new scientific areas and work across teams.
- Hands-on experience with mammalian cell culture procedures.
- Solid theoretical background in cell biology and physiology.
- Operation of automated small-scale bioreactors and/or bench-top reactors.
- Experience with perfusion process es.
- Writing and reviewing technical documents with a basic understanding of regulatory requirements
- Programming experience (e.g. Python, Mat lab , Visual Basic, etc)
- Statistical analysis
At GSK, we have already delivered unprecedented change over the past four years, improving R&D, becoming a leader in Consumer Healthcare, strengthening our leadership, and transforming our commercial execution. Now, we're making the most significant changes we've made to our business in over 20 years. We're on track to separate and create two new companies in 2022:
New GSK with a leading portfolio of vaccines and specialty medicines as well as R&D based on immune system and genetics science; and a new world-leading consumer healthcare company of loved and trusted brands.
With new ambition comes new purpose. For New GSK, this is to unite science, talent, and technology to get ahead of disease together - all with the clear ambition of delivering human health impact; stronger and more sustainable shareholder returns; and as a new GSK where outstanding people thrive.
Getting ahead means preventing disease as well as treating it. How we do all this is through our people and our culture. A culture that is ambitious for patients
- so we deliver what matters better and faster; accountable for impact
- with clear ownership of goals and support to succeed; and where we do the right thing
. So, if you're ready to improve the lives of billions, join us at this exciting moment in our journey. Join our challenge to get Ahead Together.
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