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Postdoctoral Associate- Computational Single Cell and Spatial Biology

Baylor College of Medicine
Houston, Texas
Closing date
Dec 6, 2022

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Life Sciences, Biology, Cell Biology, Computational Biology
Position Type
Full Time
Job Type
Organization Type

We are hiring a Postdoctoral Associate in the Lester and Sue Smith Breast Center at Baylor College of Medicine. The Breast Center is a collaborative environment dedicated to breast health and disease research, as well as prevention, diagnosis, and treatment of different forms of breast cancer. We are looking for a candidate with a background in computational biology/bioinformatics who thrives in collaborative research.

Job Duties

  • Works in a new laboratory headed by a computational biology principal investigator.
  • Integrates various modalities of single-cell sequencing data and spatial genomics data to better understand the contribution of spatial multi-cellular environments to cancer formation, progression, and treatment.
  • Contributes to the development of new methods or in the advancement of biological knowledge
  • Chooses to focus on one of following:
    • Methodological development. The candidate will develop innovative methods to integrate multiple modalities of single cell data to disentangle cell-to-cell variability, and identify novel cell subpopulations that have specific properties in cancer. Methods range from statistical, computational, to machine-learning based. These new methods are expected to benefit the community at large by being broadly applicable to different data and problems.
    • Applied computational biology. The candidate will use a range of bioinformatics tools to analyze research data in order to glean interesting mechanistic insights during development and cancer progression, and treatment resistance. The candidate is expected to have excellent collaborative skills as he/she is expected to work alongside biologists and clinicians from other laboratories to make impactful discoveries.
  • Participates in the writing of research papers and grants.
  • Keeps abreast of latest research findings in journals and conferences.
  • Summarizes research findings using sound statistics and informative plots/figures.
  • Presents results in lab meetings and to collaborators.
  • Collaborates with investigators in the breast center.
  • Works together with other bioinformatic tools developers in the laboratory in implementing algorithms and software packages.
  • Downloads data from repositories (GEO) for public data integration, interrogation, and hypothesis generation.

Minimum Qualifications

  • MD or Ph.D. in Basic Science, Health Science, or a related field.
  • No experience Required.

Preferred Qualifications

  • Doctoral degree in Computer Science, Management Information Systems, Information Technology, or a related field.
  • Excellent communication, written, interpersonal, and critical thinking skills.
  • Comfortable working with large-scale datasets (single cell and imaging data), and working in the high-performance computing (HPC) environment.

Baylor College of Medicine requires employees to be fully vaccinated -subject to approved exemptions-against vaccine-preventable diseases including, but not limited to, COVID-19 and influenza.

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.



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