Postdoctoral Position on role of neurovascular units in Alzheimer's Disease

A postdoctoral fellowship opportunity is currently available in the Division of Neurotoxicology, National Center for Toxicological Research (NCTR) of the U.S. Food and Drug Administration (FDA). It is located on Jefferson Laboratories Campus in Jefferson, Arkansas.

The successful candidate will collaborate directly with the Principal Investigator (PI) in a multi-disciplinary research effort and be trained in: (a) examining the role of vascular dysfunction in brain transgenic rodent models of Alzheimer’s disease (AD) and the role of diet and its relevance to human AD; (b) comparative analysis of intestinal and neuronal pathology for biomarker identification and its correlation with the microbiome in AD using transgenic rats and postmortem human tissues. The primary training opportunities of this appointment will be to conduct research using various techniques available in the NCTR's Division of Neurotoxicology, analyze data from these experiments, assist with neuropathological/neurochemical assays, present findings at scientific meetings, and publish results in respected scientific journals.

The qualified candidate should be currently pursuing or have received a doctoral degree in one of the relevant fields (Neuroscience, Toxicology/Genetic Toxicology, Cellular and Molecular Biology, Pharmacology, Neuropharmacology Biomedical Science). Degree must have been received within five years of the appointment start date.

Preferred skills:

• Experience in immunohistochemistry, basic histology techniques, animal handling, neuroimaging, and microscopy
• Previous experience in cellular and molecular biology methods (Western blot, PCR, ELISA, immunocytochemistry) 
• Basic knowledge of Alzheimer’s disease
• Candidate should be highly motivated with demonstrated excellent written and oral communications skills and the ability to work as part of a multidisciplinary team.