Postdoctoral Associate- Genomics and Bioinformatics

Summary

An open position for a Postdoctoral Fellow in human molecular genetics/genomics field is available in the laboratory of Rinki Ratnapriya, Ph.D. at the Department of Ophthalmology, Baylor College of Medicine, Houston, TX.

The Ratnapriya lab focuses on harnessing the power of genomic technologies to address translational and clinical bioinformatic challenges pertaining to retinal and macular degenerative diseases. We are working towards understanding the role of non-coding cis-regulatory sequence variation in context of retinal diseases. We generate multiple high-throughput functional genomics data sets on the genome, epigenome, and transcriptome in disease-relevant tissues/cells and use of computational approaches to integrate and analyze this data to identify the molecular components and the structure of the regulatory apparatus underlying gene expression variation. The successful applicant will work developing and applying genomic technologies that can aid in improving gene discovery and genetic diagnosis in retinal degenerative diseases. The position will focus heavily on analysis of high-throughput bulk and single-cell multi-omic data (ATAC-seq and RNA-seq) in ocular tissues. The applicant should have strong programming (Python and R) skills and some molecular biology background. The candidate must demonstrate scientific productivity, rigor and creativity with a strong publication record in peer-reviewed scientific journals.

To apply for the position, qualified candidates should submit a one-page cover letter stating reasons for their scientific interest in the lab, career goals, a curriculum vitae including technical skills, and the names and contact information of three references.

BCM is an internationally renowned medical and research institution that attracts students from around the world. BCM consistently ranks among the top of the nation's 147 medical schools with U.S. News and World Report placing the College 22nd in its annual survey of best medical schools for research and 4th for primary care in 2019.

Job Duties

• Plans, conducts and analyzes research projects.
• Dissociates human/model organisms tissue samples and prepares them for next-generation sequencing (NGS) compatible experiments.
• Designs, implements, and operates bioinformatics pipelines using existing analytical tools for NGS applications.
• Applies intellectual curiosity and passion for applying data science to biomedical problems.
• Summarizes, visualizes, and communicates research and analyses findings to principal investigator and for research publications in scientific journals.
• Responsible for laboratory operations and supervising research staff.

Minimum Qualifications

• MD or Ph.D. in Basic Science, Health Science, or a related field.
• No experience required.

Preferred Qualifications

• MD or Ph.D. in human genetics, genomics, bioinformatics, computational biology, statistics or other related field.

Baylor College of Medicine requires employees to be fully vaccinated -subject to approved exemptions-against vaccine-preventable diseases including, but not limited to, COVID-19 and influenza.

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.

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PD; CA; SN