Postdoctoral and Research Associate Positions

Postdoctoral and Research Associate Positions

University of Pennsylvania Perelman School of Medicine

Department of Cancer Biology

The institution supports innovative research on cancer, leading-edge care that is delivered in a compassionate manner, and the education of professionals who share a commitment to innovative research.

Postdoctoral and research associate positions are available immediately to develop novel cancer immunotherapy, i.e. chimeric antigen receptor (CAR)-expressing T cells,  to eradicate human neuroendocrine tumors (NETs) and gastrointestinal cancers as well as acute myeloid leukemia (AML), and investigate the unique molecular mechanisms on how CAR constructs, including the binders and the signaling domains, improve the T cell antitumor activity to eliminate solid tumors. These positions require experience in molecular cell biology or immunology and ideally experience with various mouse tumor models and flow cytometry analysis. Experience in T cell biology is valuable. The candidates should have a Ph.D. or equivalent degree. Successful applicants will have rich opportunities to gain a broad range of cutting-edge knowledge and experience ranging from synthetic biology, genome wide CRISPRa screening, immunology, bioinformatics, immunotherapy models as well as bench side to bedside translational studies. They will have opportunities to write grant proposals and enjoy a vibrant and highly interactive environment integrating cancer biology, immunology, translational immunotherapy ongoing at Penn campus that promote their career advancement.  Research work and directions can be found in the related published papers and website  (https://pubmed.ncbi.nlm.nih.gov/35314826/; https://pubmed.ncbi.nlm.nih.gov/31951650/; https://www.med.upenn.edu/apps/faculty/index.php/g275/p10254). Highly motivated candidates are encouraged to apply and send their curriculum vitae and letters from two references to:

Xianxin Hua, M.D., Ph.D.

Professor of Cancer Biology

University of Pennsylvania School of Medicine

Email: huax@pennmedicine.upenn.edu