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Scientist, Molecular Discovery

La Jolla, California
Closing date
Jul 8, 2022

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Life Sciences, Molecular Biology, Physical Sciences, Chemistry
Position Type
Full Time
Job Type
Staff Scientist
Organization Type
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Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

Role Summary

BioMedicine Design of Pfizer Inc. is seeking a highly motivated scientist for antibody display library generation and antibody discovery in La Jolla, CA. In this vital role, you will directly contribute towards our efforts for biologic therapeutic discovery and optimization. You will have access to state-of-the-art antibody discovery and optimization technologies and advanced automation equipment. Your ability to plan will help in preparing short-term work activities on projects. Your creativity in developing novel processes and new ideas will be used frequently. It is your innovative scientific temperament that will help in making Pfizer ready to achieve new milestones and help patients across the globe.

Role Responsibilities

Primary responsibilities include but not limited to:
  • Perform library construction, panning and screening to identify desirable molecules against diverse targets
  • Perform NGS amplicon preparation and coordinate with NGS related experiments
  • Trouble-shoot and optimize protocols and propose creative solutions to improve efficiency to existing processes.
  • Interpret and summarize experimental data. Participate in the evaluation of new methods or technologies.
  • Maintain detailed records of all experiments in ELN and using in-house databases and tracking systems in a detailed and descriptive manner.
  • Purchasing and management of consumable stocks, as necessary for the workflow.

  • MS in biological sciences with over 2 years experience in an academic or industrial setting.
  • BS in Biological Sciences with over 6 years of experience in an academic or industrial setting
  • Knowledge in antibody library generation is essential.
  • Experience with antibody library technology including hands-on-skills in the performance of library generation, antibody screening and amplicon preparation for NGS.
  • Extensive experience with multiple antibody screening assays and analysis, such as ELISA and FACS. Experience with cell sorting, liquid handling, and automation is desired.
  • Experience in molecular biology techniques e.g. primer design, PCR, site directed mutagenesis, antibody reformatting.
  • Good organizational skills, with scientific rigor and critical thinking.
  • Effective resource and time management is essential.

Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development

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