The Pagliarini Lab at Washington University School of Medicine in St. Louis is seeking a Staff Scientist to assist with projects related to exploring mitochondrial protein function. In particular, we are interested in candidates with extensive experience in areas including protein biochemistry and purification, enzyme assay development, mammalian cell culture and genetic (e.g., CRISPR-based) screening, and general molecular and cellular biology skills. The scientist in this position will work closely with other members of the Pagliarini Laboratory on collaborative projects exploring mitochondrial and related metabolic functions.
This position assists in developing and conducting research projects, including experiment design, data analysis and documentation of experiment results.
Primary Duties & Responsibilities
- Following instructions and discussions with the principal investigator, designs research protocols, including developing procedures for the collection, verification and management of data.
- Assists with grant preparation and reporting.
- Performs complex statistical analysis of data collected and writes interpretative reports. Verifies the correctness of the data submitted and makes recommendations based on these analyses.
- Documents research topics and prepares and submits papers based on research work to publications and committees for publication or presentation to peers.
- Solves practical problems relating to difficulties with equipment or test subjects. Suggests technical or procedural improvements in testing methods.
- Conducts literature searches related to research project.
- Performs other duties as assigned.
This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.
- Some level of training in biochemistry and metabolism with advanced communication and interpersonal skills is strongly preferred.
- Analytical, reasoning and problem-solving skills.
- Ability to analyze and interpret statistical data and to communicate data in a clear, concise manner.
- Computer literacy, including the ability to use a variety of software packages to analyze data.
Master’s degree with four years of experience in research lab operations or an equivalent combination of education and experience equaling nine years.