Senior Associate Scientist, LCMS Biomeasures

Why Patients Need You

Everything we do, every day, is in line with an unwavering commitment to the quality and the delivery of safe and effective products to patients. Our science and risk-based compliant quality culture is flexible, innovative, and customer oriented. Whether you are involved in development, maintenance, compliance or analysis through research programs, your contribution will directly impact patients.

What You Will Achieve

• You will be contributing to the development and implementation of tissue based bioanalytical assays that use state-of-the-art targeted proteomic end point detection to quantify transgene protein expression in mRNA/LNP and gene therapy biodistribution studies.
  
• This is an opportunity to leverage your expertise in sample preparation, automation and bioanalysis of biologicals matrices with emphasis on tissue-based bioanalysis.
  
• You will participate in all phases of mass spec laboratory operations including the development of sample preparation methods, assay execution, instrument maintenance and data analysis.
  
• This is a great opportunity to impact an exciting new area of science and learn this is rapidly expanding field.
  

How You Will Achieve

• Responsible for developing tissue based sample preparation techniques to support transgene and LNP biodistribution studies.
  
• As a strong collaborator and based on demonstrated project impact, develop deep partnerships in a matrix environment.
  
• Participate in technology development and implementation by exploring novel concepts and innovative workflows to expand the group's biomarker bioanalytical capabilities.
  
• Participate in all phases of mass spectrometry laboratory operations including instrument maintenance, the development of sample preparation and separation methods, data analysis
  
• Ensure all tasks and responsibilities are carried out according to scientific and ethical standards e.g. responsible for eWorkbook record keeping; QC and peer review of data and/or reports.
  

Qualifications

Must-Have

• BS/BA with 3+ years bioanalytical experience, ideally mostly in industry OR a MA/MS degree with 0+ years of experience
  
• General familiarity with LCMS technology and bioanalytical chemistry quantification assay development.
  
• Experience in operation of LCMS instrumentation and associated data analysis software systems
  

Nice-to-Have

• Expertise in quantitative tissue bioanalysis and extraction of large molecule methodology.
  
• Some understanding of protein biochemistry.
  
• Ability to work both independently and as part of a team, multitasking multiple programs.
  

PHYSICAL/MENTAL REQUIREMENTS

• As appropriate for lab based role.
  

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

• Lab based position requiring to perform all typical laboratory related activities
  
• Based in Andover
  
• Occasional travel to Cambridge (Kendal Square) may be required, depending on project needs
  

Other Job Details:

• Last Date to Apply for Job: May 27th, 2022
  

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Research and Development

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