Site Name: Cambridge 300 Technology Square Posted Date: Apr 20 2022 Are you energized by the challenge of shaping and accelerating the scientific expertise of a biology program? If so, this Investigator opportunity could be an exciting opportunity to consider. The Oncology Synthetic Lethality Research Unit has an opening for an In Vivo Pharmacologist at its Cambridge, MA site. The successful candidate will work together with a highly motivated team to discover and develop novel oncology drugs with a clear genetic relationship to cancer. The primary responsibility of this position will be to represent in vivo pharmacology in various project teams and lead the in vivo strategy to move the program forward. The candidate should be able to independently execute on a variety of in vivo techniques used to evaluate a compound in mouse tumor models and deliver high quality data. The candidate must be proficient in planning, executing and analyzing data to effectively achieve project goals and timelines. Why you? Basic Qualifications: B.S. or M.S. degree inthe life sciences field Ten or more year of In Vivo experience At least two years of experience in design, conduct, and analyze data from in vivo pharmacology studies. Preferred Qualifications: PhD in Cell Biology, Molecular Biology, Biochemistry, Pharmacology Experience in working with vivo tumor models (Cell line derived, Patient derived and Syngeneic mouse models). Expertise in techniques including- cell culture, compound preparation and formulation, administration to mice (i.v., s.c., p.o.), tumor implantation and measurements Demonstrated expertise including PK/PD, efficacy and biomarker studies to inform patient selection strategies, dose and schedule optimization, and identify rationale drug combinations. Ability to lead from the bench in problem solving and the development of innovative solutions. Data analytical skills using Prism Graph Pad or other softwares Excellent communication and presentation skills A proven track record of high productivity and scientific publications in peer reviewed journals. Strong organizational skills and the ability to manage multiple priorities in a matrix environment. Why GSK? At GSK, we have already delivered unprecedented change over the past four years, improving R&D, becoming a leader in Consumer Health, strengthening our leadership, and transforming our commercial execution. Now, we're making the biggest changes we've made to our business in over 20 years. We're on track to separate and create two new companies in 2022: New GSK with a leading portfolio of vaccines and specialty medicines as well as R&D based on immune system and genetics science; and a new world-leading consumer healthcare company of loved and trusted brands. With new ambition comes new purpose. For New GSK, this is to unite science, talent and technology to get ahead of disease together - all with the clear ambition of delivering human health impact; stronger and more sustainable shareholder returns; and as a new GSK where outstanding people thrive. Getting ahead means preventing disease as well as treating it. How we do all this is through our people and our culture. A culture that is ambitious for patients - so we deliver what matters better and faster; accountable for impact - with clear ownership of goals and support to succeed; and where we do the right thing. So, if you're ready to improve the lives of billions, join us at this exciting moment in our journey. Join our challenge to get Ahead Together. *LI-GSK If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). 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