Research Scientist / Research Fellow

Employer
Harvard University
Location
Boston, Massachusetts (US)
Salary
Salary adjusted by experience
Closing date
Jun 12, 2022

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Epigenetics, Aging, and Neurodegeneration Research Positions

Two research positions – at the level of Research Fellow, Research Scientist, Data Analyst, Computational Biologist, or Programmer – are available in the Lemos Lab at Harvard University T. H. Chan School of Public Health.

 

The ideal candidate will have a keen interest in basic and applied research themes around epigenetics, nuclear architecture, and environmental impacts on the epigenome, as well as an interest in aging and neurodegeneration.

 

The ideal candidate will have demonstrated research skills and ability to pursue research with one of the following:

  1. wet-lab experimentation, including skills with cell culturing, molecular biology, cell biology, biochemistry, epigenetic analysis, and related skills OR
  2. dry-lab computational and statistical analyses of epigenetic data, including analysis of DNA sequencing data (RNAseq, WGBS, Hi-C, etc.) and/or biomarker discovery, omic data integration, epidemiological data integration, and related skills. Requirement: proficiency in one or more statistical or scripting languages, such as R, Python, and/or Perl, appropriate for scalable data analysis.  

 

A sample of recent publications:

Wang M, Lemos B. 2019. Ribosomal DNA harbors an evolutionarily conserved clock of biological aging. Genome Research 29:325-.

Cerqueira AV, Lemos B. 2019 Ribosomal DNA and the nucleolus as keystones of nuclear architecture, organization, and function. Trends in Genetics 35:710-

Zhang et al. 2020. Exposure to microplastics cause gut damage, locomotor dysfunction, epigenetic silencing, and aggravate cadmium (Cd) toxicity. Science of the Total Environment 744:140979

Cruz J, Lemos B. 2021. Post-transcriptional diversity in riboproteins and RNAs in aging and cancer. Seminars in Cancer Biology 76:292-

Lou et al. 2021. Environmentally induced ribosomal DNA (rDNA) instability in human cells and populations exposed to hexavalent chromium [Cr (VI)]. Environment International 153:106525

Grodstein et al. 2021. The association of epigenetic clocks in brain tissue with brain pathologies and common aging phenotypes. Neurobiology of Disease 157:105428

 

Candidates should be self-motivated and able to work independently, as well as collaborate with and support other team members. Hybrid or remote work can be considered. Competitive salary commensurate with experience.

Please send the following items with your application:

  1. A research statement and cover letter describing your interests, expertise, accomplishments, and research vision (~ 1-2 pages).
  2. An updated CV.
  3. Contact information for three references.
  4. Please write “#application (your name)” in the subject line of the email.

Applications should be sent to Bernardo Lemos at blemos@hsph.harvard.edu. Emails without the hashtag “#application (your name)” won’t be delivered to the correct inbox. Informal enquiries are also welcome, though using the “#application (your name)” is also advised.

Review of candidates will begin immediately.

 

 

 

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