Why Patients Need YouOur breakthroughs would not make it to the hands of patients without our pharmaceutical manufacturing team. We rely on a team of dedicated and agile members, who understand the importance and impact of their role in Pfizer's mission. Patients need colleagues like you who take pride in their work and always look to improve outcomes. You will help to ensure that patients and physicians have the medicines they need, when they need them.
What You Will AchieveThe Pilot Plant Scientist/Engineer will be part of a diverse team of scientists and engineers focused on scale up and optimization of mammalian and bacterial fermentation, purification, and conjugation processes enabling efficient production of toxicology and process development supplies to advance Pfizer's Bio-therapeutics portfolio.
How You Will Achieve It
Responsibilities include scale-up and development of Pilot Plant processes for non-GMP production, generation of process batch records, acquisition of raw materials, and the purchase, installation, and start up of new capital equipment.
The incumbent will also be responsible for the mining and evaluation of process data, modeling, and the generation of reports to support manufacturing scale up.
Training of development personnel for safe and effective operations in the Pilot Plant and process safety assessment are also crucial.
This Associate Scientist/Engineer will collaborate on experimental studies and clinical manufacturing.
The Associate Scientist/Engineer will contribute to internally reviewed technical reports, and make presentations to scientists and management.
The Associate Scientist/Engineer will be responsible for executing operational efficiency improvements and planning and implementing improvements across Bioprocess R&D work processes.
Nice To Have:
BS or MS degree in a biological or engineering discipline, Biotechnology, Biochemistry, Biochemical Engineering, Chemical Engineering or equivalent.
Requires 0.5 - 3 years experience in biologics process development, technology transfer and/or bioprocess manufacturing.
Prior experience in a Biological Pilot Plant or Commercial Manufacturing setting is desired.
Knowledge of Biological Pilot Plant operations including cell culture and downstream processing is needed.
Thorough knowledge of Biological Pilot Plant operations including mammalian cell culture, process chromatography, ultrafiltration, and filtration and an understanding of how to scale and control these processes is needed.
Strong understanding of core principles of biotechnology, process equipment, process control, engineering concepts, material management and a broad understanding of Pharmaceutical industry practices.
Ability to work independently and adapt to rapidly changing priorities.
Understanding of continuous improvement tools (LEAN/Six Sigma, 5S, etc)
Must be capable of generating documents utilizing Microsoft Work, Excel, Powerpoint and Visio.
This position requires a highly motivated individual with the ability to work closely with other members of the BRD manufacturing team, as well as scientists from Bioprocess R&D laboratories in a matrix team environment.
Experience transferring biologics processes to pilot plants or manufacturing organizations, and knowledge of computerized and automated control systems, and data acquisition in these environments is desirable.
Prior experience in process equipment commissioning and preparation of cGMP or GLP documentation is preferred.
Demonstrated capability to work as a team member in a matrix development team.
Ability to work under minimal supervision.
Applicants must be organized, self-motivated, and capable of working independently, and in a collaborative environment.
The successful candidate will possess strong oral and written communication skills.
Strong analytical and computer skills are required. It would be advantageous for the successful candidate to have knowledge of the drug development process for progression of a biological candidate.
Dedication to maintaining and operating in a safe work environment.
Ability to lift 50lbs, torque tri clamp connections, and stand for long periods of time.Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative. EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.
Research and Development