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Discovery Analytical Technologies Lead

Groton, Connecticut
Closing date
May 18, 2022

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Life Sciences, Analytical Chemistry
Position Type
Full Time
Organization Type
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Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

What You Will Achieve

As a Senior Principal Scientist, you will be at the center of our operations and you'll find that everything we do, every day, is in line with an unwavering commitment to quality. You will be recognized as an outstanding scientist in your group. With your advanced knowledge of the discipline, you will regularly contribute in multi-disciplinary teams representing the department and influencing cross-functional teams. Your innovation is seen in way you promote the use of novel experimental approaches, create processes, hypotheses,and methodologies. You will be using your scientific judgment to adapt standard methods and techniques by applying prior work experience.

How You Will Achieve It
  • Drives Pfizer portfolio projects by leading a lab and interacting with counterparts in Discovery Sciences to deliver hit matter for novel targets; focused on, but not limited to, biophysical (binding) hit ID.
  • Drives Pfizer portfolio projects by leading a lab to deliver high quality, high throughput quantitative analytical endpoint analysis to drive Pharmacology and ADME profiling and SAR efforts.
  • Interacts within discipline across groups to advance analytical and biophysical hit ID sciences to drive Pfizer's ability to deliver the portfolio.
  • Maximizes the individual development and performance contributions of direct reports and of matrix team members.
  • Helps to define and to guide the science, culture, and evolution of the HDO Group.
  • Accountable for the professional and scientific development of direct reports.
  • Attracts, retains, and develops talent across the HDO group as a member of the HDO leadership team.
  • In partnership with counterpart scientific leaders, ensures effective use of internal and external resources of experimental labs across Discovery Sciences to deliver key portfolio impact.
  • Advances scientific and technology innovation and excellence that translate to portfolio impact and novel and enhanced workflows.

  • Doctorate level degree in analytical chemistry, biochemistry, or equivalent, with 8+ years of industrial experience, or equivalent industrial experience.
  • Track record of project and delivery of high quality high-throughput analytical experiments and data to drive project team efforts aimed at pharmacology and ADME profiling and SAR.
  • Track record of effectively designing and executing biophysical Hit ID with Analytical techniques (such as Affinity Selection by Mass Spectrometry, ASMS) to deliver useful hit matter for novel targets.
  • Track record of driving novel analytical technologies that have proved to positively impact drug discovery efforts.
  • Strong teamwork and collaboration within multi-disciplinary matrix teams leading to delivery of project objectives.
  • Demonstrated experience coaching peers and team members / direct reports.
  • Interpersonal skills to constructively challenge other scientists to ensure the group as a whole performs at a high level.
  • Ability to align, motivate, and support a team in defining and working efficiently toward project objectives.
  • Examples of presentations and peer-reviewed publications from scientific work to date.
  • Experienced in applying broad analytical chemistry and biophysics knowledge for the identification and enablement of analytical approaches that progress drug discovery projects and create and improve experimental workflows.

Additional Job Information:
  • Relocation Support Available
  • Eligible for Employee Referral Bonus


Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development
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