Leader of Spatial Omics Center of Excellence

Sanford Burnham Prebys is a preeminent, independent biomedical research institute dedicated to understanding human biology and disease, and advancing scientific discoveries to profoundly impact human health.

SBP’s NCI-designated Cancer Center seeks a leader of a planned “Center for Excellence” in spatial -omics. SBP is making a substantial investment in state-of-the-art technologies for in situ highly multiplex transcriptomic and proteomic spatial and single cell analysis, including Nanostring GeoMx, Nanostring CosMx and CODEX. The new Leader will be responsible for establishing functionality of these platforms at SBP, making them available to Institute faculty and keeping pace with new developments in this fast-moving field. The Center Leader will interface with Institute faculty and scientists, and be responsible for providing expertise, consulting, training, and high-quality service to users. In addition to spatial -omics, the Center will provide researchers a variety of NGS technologies including dissociative single-cell transcriptomics and epigenomics. The Center Leader will be responsible for providing core services, supervising the other staff members, and evaluating, developing, and implementing new state-of-the-art technologies that can expand the Center’s capabilities and staff.  The Leader will also oversee investigator training and outreach, operating and maintaining equipment, and developing/monitoring the Center’s usage and budget.

Primary Responsibilities

• Oversees daily Core operations and equipment, as well as providing genomics services
• Assists scientists with project conceptualization, technical design, execution, analysis and interpretation of data; collaborates with other SBP Cores including Bioinformatics
• Maintains cutting edge genomics technologies, recommends new technologies, adapts the Core to meet the needs of the Institute including single-cell transcriptomics and epigenomics and spatial -omics (transcriptomics and proteomics, initially).
• Ensures the core provides a high level of quality service to users
• Establishes collaborative interactions with external genomics Cores, exchanging best practices to expand the genomics resources available to SBP investigators
• Prepares annual budget and monitors expenditures and revenue throughout the fiscal year
• Operates and oversees the maintenance of Core equipment and software
• Participates in grant writing, supports grant proposals with letters of support
• Engages in outreach to inform investigators of Core capabilities - provides and organizes technical presentations, as well as producing updates for websites, brochures, and newsletters.
• Maintains the sustainability of the Core and expands its capabilities by reaching out to academic and industry clients and establishing fee-for-service projects with these partners
• Oversees core staff training and development, supervision, and evaluation

Required Experience

• Requires a PhD in a relevant scientific discipline and a minimum of three years of cumulative, progressive postdoctoral and/or industry experience in genomics, epigenomics or transcriptomics, or an equivalent combination of education, training, and/or experience from which comparable knowledge, skills and abilities have been attained
• Demonstrated experience as an accomplished team member performing genomics analysis in an academic environment, core facility, or in the private sector, and proven ability to implement new technologies
• Must have a demonstrated in-depth understanding of the theory and practice of next-generation sequencing, from library preparation to sequencing to initial data quality control, and the ability to independently design and perform a variety of experiments
• Requires the ability to simultaneously manage a variety of large, complex projects and the ability to effectively perform duties and tasks independently as well as in large, collaborative teams
• Previous experience in single-cell transcriptomics is strongly preferred, with experience in spatial transcriptomics a strong plus.
• Proof of full COVID-19 vaccination

Knowledge, Skills, and/or Abilities

• Work independently as well as in a team environment
• Be responsible, organized, and a problem solver
• Possess strong attention to detail, analytical, time management, organizational, communication, and interpersonal skills
• Professional proficiency in Microsoft Office
• Embody the Institute’s core values of Commitment, Collaboration, Communication, Community and Compassion                                                                                                                                                                                                         

  The scientists at Sanford Burnham Prebys Medical Discovery Institute are making research breakthroughs in cancer, neuroscience, immunology, and children's disease. We are also at the forefront of finding solutions for emerging health threats such as COVID-19, where we are working to identify drugs that may help millions of people. During our more than 40 year history, we have established an NCI-designated Cancer Center, designed one of the most sophisticated drug discovery centers in the nonprofit world, and created global collaborations that are leading to preventions, treatments and cures to improve human health. 

  Sanford Burnham Prebys Medical Discovery Institute is an Equal Opportunity Employer – M/F/Veteran/Disability – committed to the hiring, advancement and fair treatment of all individuals. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, or any other protected status as designated by federal, state or local law.  For additional information about your rights as an applicant, click HERE.