Principal Scientist, Analytical Development PSSM Innovative Flex Team

Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most.

What You Will Achieve

As a Principal Scientist in the Pharm Sciences Small Molecule (PSSM) Innovative Flex Team, you will play an important role during all phases of pharmaceutical development. This colleague will take an active role by leading the analytical development strategies and performing lab work to help advance our pipeline. You will work with cross-functional development teams globally (US, UK, and India) and apply a variety of methodologies to support physical and chemical characterization of drug products.

This is for an Analytical Development Principal Scientist role in the PSSM (PharmSci Small Molecule) group within Pfizer at the Lake Forest, IL site supporting either (or both) oral dosage and parenteral dosage formulations. They independently perform all analytical assignments with minimal to no instruction and can troubleshoot most analytical methods and instrumentation. They also routinely design complex experiments that lead to a fundamental understanding of pharmaceutical stability characteristics as a function of the designated drug delivery system and makes routine use of scientific literature. The role also requires a strong understanding of GLP and GMP concepts and has good understanding of the disciplines beyond chemistry and pharmaceutics that play into drug development, including IP protection, regulatory strategy, process technology, digital advancements, etc.

How You Will Achieve It

• Applies expert knowledge of multiple analytical techniques and instrumentation to independently plan analytical/process development experiments and activities to meet established project goals and timelines.
• Leads/participates in key initiatives to enhance digital capabilities within the drug development process.
• Independently develops analytical methods or techniques.
• Independently performs method qualification, verification and/or validation activities.
• Independently producing protocols and reports for analytical method development, stability or formulation/process development reports, and raw material/control/procedural monographs as required.
• Routinely designs complex experiments that lead to a fundamental understanding of drug's stability characteristics as a function of the designated drug delivery system.
• Serves as SME and represents the department at internal and external meetings; Interacts with peers outside of the department in a multi-faceted team approach to drug development.
• Educates and trains other group members on using and troubleshooting all analytical methods and instrumentation.
• Mentors, coaches, guides, and develops junior scientists.
• Makes routine use of scientific literature. Has a good understanding of the disciplines beyond chemistry and pharmaceutics that also play into drug development including IP protection, regulatory strategy, process technology, etc.
• Directly or through others, leads and supports analytical for complex drug product projects from concept up to commercialization.
• Leads and supports method transfers to internal and external testing labs.
• Works directly with parties beyond department, including but not limited to 3rd party analytical labs, CMOs, and involvement with other divisions of Pfizer.

Qualifications

Basic Qualifications

• PhD in Chemistry, Biochemistry, Pharmaceutics, Chemical Engineering or related field and at least 4 years of analytical development experience (HPLC, UHPLC, GC, Mass Spectrometry, KF, Dissolution, wet chemistry, etc.) supporting pharmaceutical development of parenteral and/or oral dosage drug products
• M.S. in Pharmaceutics, Biochemistry, Chemistry, Chemical Engineering or related field and at least 9 years of analytical development experience (HPLC, UHPLC, GC, Mass Spectrometry, KF, Dissolution, wet chemistry, etc.) supporting pharmaceutical development of parenteral and/or oral dosage drug products
• BS in Pharmaceutics, Biochemistry, Chemistry, Chemical Engineering or related field and at least 12 years of analytical development experience (HPLC, UHPLC, GC, Mass Spectrometry, KF, Dissolution, wet chemistry, etc.) to support pharmaceutical development of parenteral and/or oral dosage drug products
• Written and oral communication skills and the use of MS Office (Word, Excel) are required.
• High proficiency in advanced digital tools and technology.
• Experience in coaching or developing junior scientists
• Experience leading small projects
• Ability to collaborate
• Able to thrive in a dynamic, ever-changing environment

Preferred Qualifications

• cGMP laboratory experience is highly preferred
• Advanced analytical experience (GC-MS, LC-MS, etc.) is highly desirable.

Physical/Mental Requirements

• This position involves frequent work within an analytical testing lab, in the presence of chemicals, with appropriate Personal Protective Equipment (PPE). Occasional work within a potent compound analytical laboratory - using isolator or other safety technology.

Non-Standard Work Schedule, Travel or Environmental Requirements

Expected travel 5 -10%

Additional Posting Information

• Eligible for Employee Referral Bonus
• Eligible for Relocation Support

#LI-PFE

Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development