Site Name: USA - Maryland - Rockville Posted Date: Mar 8 2022 This is an exciting opportunity for a brilliant PhD level scientist to join a world leading Vaccines Research & Development environment. You'll be channeling your passion for science and helping to revolutionize the future of Vaccines R&D at GSK whilst fostering strong foundations for a career in cutting edge science. Do you want to be part of a company investing in scientific and technical excellence to develop a pipeline of new products to meet the needs of patients across world? Please read on for more details on this unique opportunity and details on how to apply. About Vaccine R&D As vaccine development has advanced, new types of vaccines have arisen, presenting challenges in characterization and further linking characteristics to function. However, recent development of vaccines against current pandemics or more complex diseases such as has met difficulties. In addition, the gaps in our knowledge on protective responses against pathogens are a significant barrier to ideal vaccine design and are often associated with increased risk of clinical failure. What is Vaccines Scientific Leaders Programme? The Scientific Leaders Programme in Vaccines is a 2-year global programme which builds a pipeline of scientists with the right expertise, technical capabilities and behaviors to drive the future in Vaccines Research and Development. How does the Vaccines Scientific leaders Programme work? You will spend two years working on a key development project, contributing to key strategic areas of our Vaccines R&D business. We have three location options; Italy, Belgium or US which aligns to our Vaccine R&D hubs. Working on challenging projects will provide you with in-depth knowledge of the ways in which Science and Technology is being applied across R&D in GSK. All associates will be contributing to our mission to improve the quality of human life, by enabling people to do more, feel better and live longer - all while fostering strong foundations for a future career in science. Is the Vaccines Scientific leaders Programme for you? This is a scientific/technical leadership position where you will be empowered to be innovative, collaborative, decisive and bold to solve novel R&D problems. On completion of the 2-year programme we aim to bring you on-board into available technical leadership roles that best suits business' needs and your abilities. We need Scientific leaders to help embed modern Scientific principles and ways of working within the vaccines R&D organisation. You will do this through: Project Title: Next Generation High-Throughput Screening of RNA Vaccine Candidates Project proposal: Vaccine research is currently undergoing a technological revolution that is enabling the accelerated development of new vaccines and rapid response to public health needs. The successful candidate will become a leader in GSK's effort to develop new strategies for the high-throughput screening of RNA vaccine candidates within Preclinical Research and Development. This work will expand our fundamental understanding of RNA vaccine platforms, contribute to the design of next generation RNA vaccines, and enable the rapid selection of optimal RNA vaccine candidates on short timelines. Responsibilities: Within the Preclinical Vaccine Design and Cellular Immunology group, you will design, manage, and implement high-throughput screening assays to measure the performance of RNA vaccine candidates. You will consider both the properties of the RNA vector and protein antigen expressed in highly paralleled and miniaturized assays. You will also collaborate directly with both internal and external stakeholders to advance our capabilities for the organization and analysis of large datasets, implementation of new technologies for the automation of lab experimentation, and analysis of the resulting data to increase our fundamental understanding of RNA vaccines. You will be expected to contribute to the project by proposing research strategies, updating relevant knowledge, communicating project results (internally and externally), and writing scientific communications. To be successful in this role you should have: PhD in Biochemistry, RNA biology, or Cell biology *critical Expertise in cell culture and cell-based assays * critical Strong experience with molecular biology and the production/handling of RNA * critical Experience with microplate readers, fluorescence assays, and/or protein characterization assays * critical Be highly organized, able to handle large datasets, and deal with complexity * critical Understanding of proteins, antibodies, and vaccine antigen design Understanding of the design and properties of RNA vaccines Hands-on experience in the implementation of lab automation is highly preferred Strong problem-solving, prioritization, and self-directional abilities Excellent written and oral communication skills in English. Ability to convey scientific messages across multidisciplinary functions Excellent interpersonal skills. Demonstrated ability to work in collaborative teams. Available Location: US - Rockville, Maryland We recommend you apply as soon as possible, because we accept ongoing applications and will close this vacancy once we have enough applications. #SLP *LI-GSK If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. At GSK, the health and safety of our employees are of paramount importance. As a science-led healthcare company on a mission to get ahead of disease together, we believe that supporting vaccination against COVID-19 is the single best thing we can do in the US to ensure the health and safety of our employees, complementary workers, workplaces, customers, consumers, communities, and the patients we serve. GSK has made the decision to require all US employees to be fully vaccinated against COVID-19, where allowed by state or local law and where vaccine supply is readily available. The only exceptions to this requirement are employees who are approved for an accommodation for religious, medical or disability-related reasons. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. 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