The post-doctoral fellow, research scientist or associate researcher will be engaged in translational cancer research projects focused on regulators of growth, survival and drug resistance of breast and other cancers, as well as their microenvironment, especially immune effectors. The researcher will use a broad range of approaches (genetic, cell biological and in vivo modeling) to understand how breast cancers, particularly triple negative breast cancers, resist chemotherapy treatments and metastasize. The projects also examine how anoikis resistance and epithelial-mesenchymal transition contribute to the growth and metastases of triple negative breast cancers. The researcher will utilize patient-derived xenograft models of breast cancer and organoid cultures to screen and validate novel therapeutic strategies. The researcher will also study how the immune microenvironment regulates response of breast and other cancers to chemotherapy/targeted therapies. Background in cancer cell biology/models, genetics, molecular biology, biochemistry, or immunology required. Experience with animal tumor models strongly preferred.
For postdoctoral fellow, MD, PhD or MD/PhD degree required. For associate researcher, minimum BA/BS degree, MA/MS preferred.