Staff Scientist - Tumor Heterogeneity During Development of Resistant Cancer

About City of Hope

City of Hope is an independent biomedical research and treatment organization for cancer, diabetes and other life-threatening diseases.

Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope's translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution. AccessHope™, a subsidiary launched in 2019 serves employers and their health care partners by providing access to City of Hope's specialized cancer expertise.

A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation's "Best Hospitals" in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.

City of Hope's commitment to Diversity, Equity and Inclusion

We believe diversity, equity and inclusion is key in serving our mission to provide compassionate patient care, drive innovative discovery, and advance vital education focused on eliminating cancer and diabetes in all of our communities. Our commitment to Diversity, Equity and Inclusion ensures we bring the full range of skills, perspectives, cultural backgrounds and experiences to our work -- and that our teams align with the people we serve in order to build trust and understanding. We are dedicated to fostering a community that embraces diversity - in ideas, backgrounds and perspectives; this is reflected in our work and represented in our people.

Position Summary

A Staff Scientist position is available in the laboratory of Dr. Andrea Bild at the City of Hope Cancer Institute. We are looking for a creative and motivated individual to work on a project associated with breast tumor heterogeneity, subclonal evolution, and response to drug therapy. This individual must have good project coordinating skills and must be able to manage a team of scientists. This funded project is part of the prestigious Cancer Systems Biology Consortium: https://www.cancer.gov/about-nci/organization/dcb/research-programs/csbc and provides an opportunity to lead systems biology focused projects and interact with leaders in the field.

Key Responsibilities include:

• The scientist will study the evolution of tumor heterogeneity during development of resistant cancer.
• Research can leverage our impressive series of patient cells and isogenic cell lines for drug screening and oncogenic signaling determination.
• The scientist will work closely with the PI in developing and implementing the project, together with a team of medical oncologists, systems biologists, mathematicians, and biologists.
• The collaborative environment at the City of Hope and the discovery-based nature of this project will foster multidisciplinary thinking and will provide the potential for advancing expertise in cutting-edge technologies.

Basic education, experience and skills required for consideration:

• A Ph.D. degree in cellular and molecular biology, systems biology, or related discipline
• Must have multiple first author publications

Additional Information:

As a condition of employment, City of Hope requires staff to comply with all state and federal vaccination mandates.

• For more information about Dr. Andrea Bild's research, please click here.
• When applying for the position, please include a cover letter with a statement of research interests and how they relate to this project, an updated CV and contact information for 3-5 references.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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