Postdoctoral Fellow- Immuno-Oncology

About City of Hope

City of Hope is an independent biomedical research and treatment organization for cancer, diabetes and other life-threatening diseases.

Founded in 1913, City of Hope is a leader in bone marrow transplantation and immunotherapy such as CAR T cell therapy. City of Hope's translational research and personalized treatment protocols advance care throughout the world. Human synthetic insulin, monoclonal antibodies and numerous breakthrough cancer drugs are based on technology developed at the institution. AccessHope™, a subsidiary launched in 2019 serves employers and their health care partners by providing access to City of Hope's specialized cancer expertise.

A National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network, City of Hope is ranked among the nation's "Best Hospitals" in cancer by U.S. News & World Report and received Magnet Recognition from the American Nurses Credentialing Center. Its main campus is located near Los Angeles, with additional locations throughout Southern California and in Arizona.

City of Hope's commitment to Diversity, Equity and Inclusion

We believe diversity, equity and inclusion is key in serving our mission to provide compassionate patient care, drive innovative discovery, and advance vital education focused on eliminating cancer and diabetes in all of our communities. Our commitment to Diversity, Equity and Inclusion ensures we bring the full range of skills, perspectives, cultural backgrounds and experiences to our work -- and that our teams align with the people we serve in order to build trust and understanding. We are dedicated to fostering a community that embraces diversity - in ideas, backgrounds and perspectives; this is reflected in our work and represented in our people.

Position Summary: Our group in the Department of Immuno-Oncology of the Beckman Research Institute at the City of Hope is interested in developing novel therapeutics for the treatment of difficult-to-treat malignancies occurring in the pancreas, lung and blood. We are currently exploring cancer vaccines to elicit immunity capable of eliminating cancers over-expressing tumor-specific antigens. The successful candidate will participate in laboratory research by performing bacterial, molecular, and mouse work to develop, characterize and evaluate efficacy of candidate agents.

Key Responsibilities include, but are not limited to:

• Recombinant bacterial maintenance
• Protein expression analysis
• Flow cytometric analysis
• Mouse handling (injections, collection of blood and tissues)
• Cell culture maintenance and assays involving mouse and human primary T cells (mouse splenocytes, mouse and human PBMCs)

Qualifications: Education, experience and skills required for consideration:

• Ph.D. in immunology, microbiology or related disciplines
• Meticulous record keeping, impeccable organization and proficiency with databases
• Exceptional organizational skills
• Excellent written and verbal communication
• Strong work ethic, highly motivated, and work well independently and in a team
• Hands-on experience in various dosing routes to mice and collecting blood and tissues, as well as processing samples for ex vivo analysis
• Extensive hands-on experience in primary T-cell culture and assays (mouse and human)
• Experience in imaging, flow cytometry and translational science

Background in cancer models and therapeutics is a plus.

Additional Information:

• To protect the health of patients and staff and to comply with new State of California mandates, City of Hope staff are required to show proof of full vaccination by September 30, 2021. Compliance is a condition of employment.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.