AREA OF RESEARCH: Redox processes, metabolism and lung fibrosis
Lung fibrosis is a devastating disease that kills people 3-5 years post-diagnosis. It results from repeated micro-injuries to distal lung epithelial cells and their inadequate repair. Changes in energy metabolism and increases in the oxidative environment are critical in disease pathogenesis. Emerging studies point to a connection between these processes and how they affect the fate of distal lung epithelial cells. A post-doctoral position is open to examine the interplay between reconfiguration of metabolism, glutathione-based protein oxidations and control of epithelial cell plasticity. This project extensively utilizes organoid cultures, gene-edited mouse models, primary cells from IPF subjects, and redox proteomics/biochemistry strategies.
The research environment in the Redox Biology and Pathology program at Vermont Lung Center is highly collegial and interactive, spanning multiple disciplines of bioinformatics, chemistry, lung biology, and clinical care.
A strong emphasis is placed on mentoring, career advancement and academic independence.
4 seasons, with summer swimming/sailing/hiking and winter sports
Great work life balance
Strong emphasis on diversity, equity, and inclusion
Opportunities for career advancement
FOR INFORMATION: Contact Yvonne Janssen-Heininger at Yvonne.email@example.com