Postdoctoral positions in Neurodegeneration

Postdoctoral positions in Neurodegeneration

Several NIH funded postdoctoral/staff positions are available to study the biology of neurodegeneration. The broad goals of this project are to study mechanisms underlying the pathogenesis of genetic neurological disorders with a view to seek out avenues for therapy.

We use an array of techniques from cell biology and biochemistry to bioinformatics and mouse genetics to understand the molecular basis of neuronal dysfunction. Our work utilizing multiple techniques to study different neurological diseases is highlighted in some of our recent publications on genetic ataxias and other degenerative conditions (Cvetanovic M, et al. Nature Medicine, 2011; Israeli E, et al. HMG, 2016; Edamakanti CR, et al. JCI, 2018; Frederick NM, et al. HMG, 2018; Hu YS, et al. Brain, 2019, Edamakanti CR, et al. Mov Disord, 2021; Brooker SM, et al. Ann Clin Transl Neurol, 2021).

The applicant will work in a state-of-the-art laboratory in a stimulating intellectual and collaborative environment provided by the Northwestern University Interdepartmental Neuroscience Program and the Davee Department of Neurology. The laboratory is located in the downtown Chicago campus of Northwestern University, just off the “Magnificent Mile”.
 

We are looking for highly motivated individuals who thrive on intellectual challenges. Applicants must have a PhD or MD degree and a strong background in biochemistry, cell biology and molecular biology.  We also welcome applications from senior scientists if they bring special grant writing or technical skills.

Familiarity with any of the following areas is a plus (but not necessary): iPS technology  with differentiation of stem cells into neurons and astrocytes, autophagy research, protein clearance and quality control pathways, cell biology of primary neurons, endothelial cells or glia in culture, live cell imaging or super-resolution microscopy, the cell biology of lysosomes, mitochondria or the cytoskeleton, RNAi and CRISPR based knock-down of proteins using viral vectors, RNA-Seq, protein biochemistry and cell-signaling, epigenetics, large scale proteomics, single cell gene expression and bioinformatic approaches based on mass-spec identification of proteins. We also have a translational project on biomarker development. Ultimately, however, we encourage all intellectually curious applicants with a strong drive to contact us. We have a track record of mentorship and placing our trainees in competitive faculty and industry positions.

Please submit a C.V., a brief statement of research interests and background, and the names of three references (preferably by email) to the address below:
                                     

Puneet Opal, MD, PhD
Professor
Departments of Neurology, and Cell and Molecular Biology
Northwestern University Interdepartmental Neuroscience Program
Northwestern University Feinberg School of Medicine
Email: p-opal@northwestern.edu
Northwestern

Northwestern University is an Equal Opportunity, Affirmative Action Employer of all protected classes, including veterans and individuals with disabilities. Women, racial and ethnic minorities, individuals with disabilities, and veterans are encouraged to apply.  We also welcome interest from international applicants. Hiring is contingent upon eligibility to work in the United States.