Fields of specialization: Defective mitosis, kinetochore failure, growth factor signaling, cancer cell biology, genomics, mouse models of cancer, brain tumour biology, origins of glioblastoma
Description: Dr. Gregory Cairncross and Dr. Michael Blough are recruiting a postdoctoral associate with interests in defective mitosis, the molecular origins of cancer, and growth signaling. The successful candidate will have the opportunity to join a dynamic research group studying the nature, evolution, and treatment of brain tumours in adults and children. The successful candidate will work closely with wet lab scientists to decipher how a ubiquitious growth factor abundant in the mammalian brain transforms neural progenitor cells to produce a histological and molecular replica of human glioblastoma with its 7+/10- diagnostic signature. Using this model of human GBM as a starting point, the successful candidate will have the freedom and opportunity to develop her/his own lines of inquiry supported by state-of-the-art facilities for animal and human genome research aided by a comprehensive cell and tissue bank. The long term goal of the Cairncross lab is to understand and prevent human glioblastoma.
Skills required: The successful candidate will have had superb wet lab research training in cell biology, neurobiology, cancer cell biology, or genomics, and have completed a PhD. In addition, they will have published a significant body of work in rigorous international biomedical journals. The successful candidate will also be an ambitious self-starter with creative ideas, able to work independently and with others, solve problems, and design and execute the key experiments. Experience with advanced microscopy and animal models of cancer would be invaluable skills.
Expectations: Funding is available for two years but the successful candidate will nevertheless be expected to compete for external awards and fellowships. Their most advanced degree must have been conferred within the last 3 years to retain eligibility for most major external awards.
Research environment: Research will be conducted at the Cumming School of Medicine, University of Calgary. The candidate will work alongside basic scientists and clinical scientists.
How to Apply: Submit a letter, CV, three references, and statement of research interests and aspirations (2 pages) to Gregory Cairncross, MD (firstname.lastname@example.org) or Michael Blough, PhD (mdblough@ ucalgary.ca) or mail to University of Calgary, 3280 Hospital Drive NW, HRIC 2AA20, Calgary, AB, T2N 4Z6 Canada. Closing date for applications is July 1, 2022.
Calgary: Ideally situated in the foothills of the Rockies, Calgary is Canada’s most entrepreneurial city, combining a culture of hard work with unmatched outdoor recreational opportunities.