A postdoctoral fellowship position is available at Perelman School of Medicine, University of Pennsylvania for joint projects on cardiac repair in ischemic heart disease. We aim at understanding the molecular mechanisms underlying vascular dysfunction after myocardial infarction with a focus on endothelial cell plasticity and metabolism. The goal of this study is to develop new regenerative therapeutics by targeting vascular aberrancy and reprogramming vascular niche to promote cardiac repair after myocardial infarction (Nature Cardiovasc Res 2022). We are also interested in cell therapy for cardiovascular disease by targeting macrophages or fibroblasts using CAR-T immunotherapy, a promising strategy that our laboratories have developed for treating cancer (Nature Cancer 2021). More information about the laboratories can be found at https://www.med.upenn.edu/apps/faculty/index.php/g275/p8688889 and https://www.med.upenn.edu/apps/faculty/index.php/g20002840/p8679288
Highly motivated individuals with PhD or MD in cardiology, cell biology or related fields with preference for a background in vascular biology or immunology are encouraged to apply. Practical experience with molecular and cellular biology techniques as well as animal models is required.
Applicants should send a CV, brief statement of research interests, and the names/addresses of 3 references to: Yanqing Anna Gong, PhD (firstname.lastname@example.org) or Dr. Yi Fan (email@example.com )
Competitive stipend and a generous benefits package commensurate with experience will be provided. The University of Pennsylvania is an equal opportunity, affirmative action employer. Women and minority candidates are strongly encouraged to apply.