The Wangler lab is engaged in a number of clinical research studies for patients with rare diseases and undiagnosed conditions. Particular research interests include peroxisomal disease, autism and inclusion of under-represented minorities in genomic medicine. We are seeking a motivated individual to engage in this human genetics research. The individual would aid clinical study coordinators, would be responsible for DNA samples, and would learn and use DNA sequencing software for analysis of patient samples.Job Duties
- Work with a study coordinator to contact and schedule human subjects for two large NIH funded human genetic studies. In the first study, the Community Texome project, underserved individuals who have not had access to genomic sequencing are recruited for genomic diagnostics. In the second study, the Brain Gene Registry, individuals are contacted based on gene variants identified on sequencing.
- Meet with human subjects along with M.D.in the clinic for intake exam, recruitment.
- Collect, harvest, store DNA samples using Qiagen kits for buccal, saliva and blood DNA collection.
- Use standard methods to quantify and determine the quality of the DNA.
- Perform DNA sequencing analysis using software and tools developed by our lab and team, this include MARRVEL (www.MARRVEL.org).
- Develop gene candidates for specific cases of disease. This involves assessing lists of variants and categorizing their predicted pathogenicity.
- Bachelor's degree in a Basic Science or a related field.
- Two years of relevant experience.
- Master's degree in a related field.
- Experience in clinical human trials a plus.
Baylor College of Medicine requires employees to be fully vaccinated -subject to approved exemptions-against vaccine-preventable diseases including, but not limited to, COVID-19 and influenza.
Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.