Post-doc Fellow/Researcher/Scientist, Cancer Biology, Icahn School of Medicine at Mt Sinai-Irie lab
- Employer
- Icahn School of Medicine at Mount Sinai
- Location
- NCI designated Cancer Center, Icahn School of Medicine at Mount Sinai, Irie lab
- Salary
- According to NIH guidelines and depending on years of experience
- Closing date
- Mar 2, 2022
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- Discipline
- Life Sciences, Cell Biology, Oncology, Health Sciences, Translational Research, Cancer Research
- Position Type
- Full Time
- Job Type
- Lab Manager, Postdoc, Postdoc Fellowship, Research Scientist, Senior Scientist, Staff Scientist, Technician
- Organization Type
- Academia
The post-doctoral fellow, research scientist, associate researcher or technician will be engaged in translational cancer research projects focused on regulators of growth, survival and drug resistance of breast and other cancers, as well as their microenvironment, especially immune effectors. The researcher will use a broad range of approaches (genetic, cell biological and in vivo modeling) to understand how breast cancers, particularly triple negative breast cancers, resist chemotherapy treatments and metastasize. The projects also examine how anoikis resistance and epithelial-mesenchymal transition contribute to the growth and metastases of triple negative breast cancers. The fellow will utilize patient-derived xenograft models of breast cancer and organoid cultures to screen and validate novel therapeutic strategies. The fellow/scientist will also study how the immune microenvironment regulates response of breast and other cancers to chemotherapy/targeted therapies. Background in cancer cell biology/models, genetics, molecular biology, biochemistry, or immunology required. Experience with animal tumor models strongly preferred.
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