Postdoc Position in Hedgehog signaling and primary cilia biology

A POSTDOCTORAL POSITION is available to study Hedgehog signaling in development and cancer at Weill Medical School of Cornell University. The Hedgehog (Hh) family of secreted signaling proteins plays fundamental roles in animal development, cell growth, and differentiation. Loss of the Hh signaling pathway activity results in severe developmental birth defects, whereas inappropriate activation of the Hh signaling pathway is also associated with several common types of human cancer including basal cell carcinoma (a skin cancer) and medulloblastoma (a brain tumor). Hh signaling occurs in primary cilia. Our work focuses on how defects in primary cilia formation affect Hh signaling by using a variety of approaches including molecular, cell and developmental biological, biochemical, and genetic (mouse knockout and knockin) approaches. The experimental systems used in our laboratory include in vitro, cultured cells, and mouse models. Experience in molecular and cell biology and/or developmental biology is desirable. Applicants with own funding will be considered favorably. Highly motivated candidates who are interested in this exciting research field should e-mail a cover letter, CV, & reference information to: Baolin Wang, PhD, Weill Medical College Of Cornell University. Email: baw2001@med.cornell.edu. Cornell Medical School Website is: http://www.med.cornell.edu/. EEO/AA/M/F/D/V.