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Research Associate, Pre-Clinical Bioanalytics

Spark Therapeutics
Philadelphia, Pennsylvania
Salary not provided
Closing date
Feb 26, 2022

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Health Sciences, Drug Development
Job Type
Research Scientist
Organization Type
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Job Details

The Research Associate will be part of the Pre-Clinical Bioanalytics (PCB) group, supporting multiple fast-paced non-clinical studies for advancing novel gene therapy programs across all Therapeutic Areas.

  • Perform various bioanalytical assays in support of all therapeutic areas (Discovery, CNS, Liver, and Ocular) for advancing early therapeutic programs.
  • Participate in testing research and preclinical study samples, analyze experimental data, and prepare results documents.
  • With guidance from the manager, participate in developing new research-based bioassays and optimizing existing assays using various bioanalytical techniques.
  • Collaborate within the PCB group to meet business objectives.
  • Maintain accurate, timely and detailed records of experimental work.
  • Maintain inventory of lab reagents, supplies and test samples.
  • Participate in instrument maintenance, as needed.
  • Champion all safety aspects in the Translational Research laboratories.
  • Hands-on laboratory work.
  • Perform experiments, analyze data and maintain proper documentation of experiments performed.
  • Participate in maintaining lab equipment.
  • Participate in maintaining proper inventory of lab reagents, supplies and study samples.
  • Stay current with all required lab safety and compliance training.

  • Bachelor’s degree required
  • A minimum of 3 years laboratory experience is required.
  • Broad knowledge of basic lab techniques (such as tissue culture, ELISA, ECL, and Western blot) is required.
  • Experience with immunoassays (such as biomarker, anti-drug antibody, and cell-based neutralizing antibody assay (NAb) is preferred.
  • Bioanalytical assay development experience is preferred.
  • Experience with AAV vectors is a plus.
  • Experience with basic research is a plus.
  • Strong organizational skills.
  • Excellent writing and verbal communication skills.
  • Demonstrate technical problem-solving skills of moderate to complex issues, discuss with manager and refer to policies/practices for guidance.
  • Keep accurate records, follow instructions, and comply with company policies.
  • Ability to work independently and as part of a team.
  • Attention to detail and the ability to meet deadlines.
  • Champion all safety aspects in the Translational Research laboratories.
  • Self-motivated, flexible, and willing to adapt to meet team goals.
  • Must be comfortable in the fast-paced work environment and interact with multi-disciplinary research teams

Please be aware that Spark mandates COVID-19 vaccination of all employees regardless of work location. Accommodations may be made in accordance with applicable law.

Nearest Major Market: Philadelphia

Join the Spark Team

We were born of innovation, springing from the curiosity, imagination and dedication of remarkable scientists and healthcare visionaries. Our shared mission is to challenge the inevitability of genetic disease by discovering, developing, and delivering treatments in ways unimaginable - until now.

We don't follow footsteps. We create the path.


At Spark Therapeutics, a fully integrated, commercial company committed to discovering, developing and delivering gene therapies, we challenge the inevitability of genetic diseases, including blindness, hemophilia, lysosomal storage disorders and neurodegenerative diseases.

Founded in March 2013 as a result of the technology and know-how accumulated over two decades at Children’s Hospital of Philadelphia (CHOP), our investigational therapies have the potential to provide long-lasting effects, dramatically and positively changing the lives of patients with conditions where no, or only palliative, therapies exist. Greater understanding of the human genome and genetic abnormalities have allowed our scientists to tailor investigational therapies to patients suffering from very specific genetic diseases. This approach holds great promise in developing effective treatments to a host of inherited diseases. Our initial focus is on treating orphan diseases.

Headquartered in dynamic Philadelphia, we are a diverse, experienced team united in our goal to break down barriers for people and families affected by genetic diseases. As our name suggests, our investigational, one-time therapies are designed to spark healthy biology, and deliver potentially life-altering transformation for people and families affected by genetic disease. Spark is a member of the Roche Group.

Find Us
3737 Market Street
Suite 1300
United States
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