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Senior Associate Scientist, In Vivo Pharmacology (non-PhD)

Cambridge, Massachusetts
Closing date
Jan 24, 2022

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Life Sciences, Pharmacology, Physical Sciences, Chemistry
Position Type
Full Time
Job Type
Staff Scientist
Organization Type
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Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

What You Will Achieve

As a Senior Associate Scientist, you will be at the center of our operations and you'll find that everything we do, every day, is in line with an unwavering commitment to quality. The Internal Medicine Research Unit (IMRU) is seeking a highly motivated non-PhD (Bachelor's or Master's level) Scientist with rodent handling and cell culture experience to support mechanistic and drug discovery metabolic disease related research. The ideal candidate will design and execute in vitro and in vivo experiments, and can demonstrate the ability to analyze, interpret and effectively communicate results. Candidate will work closely with manager and will collaborate with other Pfizer scientists to support IMRU portfolio projects and workgroup goals. Your significant experience of applying knowledge of principles, concepts, and practices of the discipline will make you a critical member of the team. You are proactive in contributing to all team discussions and creating an environment of collaboration. It is your hard work and focus that will help in making Pfizer ready to achieve new milestones and help patients across the globe.

How You Will Achieve It

  • Plan, design and execute in vivo experiments. Comfortable handling and dosing (IP, SC, PO and IV) rodents. Blood and tissue collection.
  • Perform cell culture experiments.
  • Conduct molecular biology experiments such as but not limited to transfection, gene expression analysis, immunostaining, ELISA and Western blotting.
  • Capable of following assay protocols and analyzing and interpreting data.
  • Compliance to laboratory safety and electronic notebook standards.
  • Working effectively with peers to support projects and workgroup goals.
  • Identify and report any experimental problems, proactively troubleshoot causative factors, and implement necessary corrections following discussion with supervisor.


  • Bachelor's or Master's degree in biology, pharmacology, biochemistry, molecular biology or other related discipline with 2-4 years of lab experience in academia or in industry
  • Hands-on rodent handling, dosing, and tissue collection experience
  • Basic laboratory skills for standard cell and molecular biology methods including but not limited to cell culture, siRNA and plasmid transfections, immunoassays such as ELISAs and western blotting, and quantitative real-time PCR
  • Ability to use appropriate software to perform analysis of data
  • Experience with experimental design and the interpretation of results; ability to troubleshoot methodologies and results
  • Effective verbal and written communication skills
  • Proficiency with personal computers, including word processing, Excel, PowerPoint and relevant scientific software
  • Excellent organization and planning skills, the ability to work in a fast-paced environment independently or as part of a team, strong motivation with a dedicated work ethic

  • Experience with some cardiac related techniques such as: Echocardiography, primary cardiomyocyte isolation, IonOptix, Imaging, Force/pCa assay, OR metabolic disease related techniques such as: treadmill running, glucose/insulin sensitivity tests, calorimetry, in vivo skeletal muscle force and fatigue measurements.
  • Knowledge of metabolism and pharmacology (i.e. cardiac or skeletal muscle physiology)
  • Drug discovery experience

  • Must be able to wear standard PPE (lab coat/safety shoes/glasses/etc).

Other Job Details:
  • Last Date to Apply for Job: January 28th, 2022

Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development

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