Site Name: USA - Pennsylvania - Upper Providence Posted Date: Jan 12 2022 Are you energized by a challenging role in the Oncology Synthetic Lethality Research Unit, where scientific demand is driving team growth? If so, this Investigator, Oncology (In Vitro Biology) role would be a great opportunity to consider. The Synthetic Lethal Research Unit within Oncology based in Upper Providence, PA is seeking an accomplished, highly ambitious scientist to make important contributions to drug discovery and biomarker development. The successful candidate will work together with a highly motivated team to discover and develop novel oncology drugs with a clear genetic relationship to cancer. More specific activities include target validation using genetic and tool molecules to define the mechanism of action of targets and compounds using biochemical, cellular, and in vivo models. This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following: 1) Be a key biology contributor to drug discovery programs 2) Identify and evaluate new drug targets 3) Discover and develop pharmacodynamic and predictive biomarkers to support translation to the clinic. 4) The scientist will work directly with external scientists as part of research collaborations, direct contract research studies, and contribute to strategic planning for the Synthetic Lethal Research Unit. 5) The candidate's industry-leading research will address important drug discovery questions, directly impact GSK Oncology's pipeline, and lead to publication in top scientific journals. Why You? Basic Qualifications: Ph.D. in cell biology, molecular biology or a related field with 3 or more years postdoctoral experience or M.S. with 6+ years industry experience. Preferred Qualifications: Experience/knowledge of tumor cell biology or cell signaling, cancer genetics, and synthetic lethal targets. Hands-on experience with genetic engineering, screen or assay development. Knowledge of how to leverage cancer genomics data and analysis methods for discovery efforts. Attention to detail, proficient reasoning skills in experimental design and execution, data analysis, statistical methods and interpretation. Adept at managing multiple priorities in an efficient and organized manner. Cancer drug discovery experience. Why GSK? Our values and expectations are at the heart of everything we do and form an important part of our culture. These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities: Operating at pace and agile decision-making - using evidence and applying judgement to balance pace, rigour and risk. Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution. Continuously looking for opportunities to learn, build skills and share learning. Sustaining energy and well-being. Building strong relationships and collaboration, honest and open conversations. Budgeting and cost-consciousness. *LI-GSK If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. 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