Postdoctoral positions are available in the Tafesse lab (https://www.ohsu.edu/school-of-medicine/tafesse-lab) at Oregon Health & Science University, Portland, Oregon.
Our lab studies host-pathogen interactions of viruses (SARS-CoV-2, HIV and flaviviruses) and bacteria (M. tuberculosis). We are especially interested in understanding 1) how pathogenic microbes use host factors such as lipids during infection, 2) studying antibody-mediated immunity elicited by vaccines and natural infections, and 3) developing nanobodies/single-domain antibodies against viral and bacterial antigens as a tool to study host-pathogen interactions and/or harness them for therapeutic and diagnostic purposes. Projects in our lab are highly collaborative and interdisciplinary in nature, combining various approaches including protein/lipid biochemistry, cell biology, microscopy and the use of various functional lipid probes. In collaboration with the Pacific North National Laboratory (Richland, Washington), we apply multi-omics (lipidomics, metabolomics and proteomics) approaches to gain insight into how human pathogens reprogram metabolic pathways during infection.
Candidates with a wide range of expertise will be considered but applicants with expertise in infectious diseases, molecular biology, and cell biology are especially encouraged to apply. Applicants with biostatistics and big data analysis should also apply. The position is open immediately and the salary is commensurate with experience. Please submit a CV and the contact information of three referees via email (tafesse at ohsu.edu)