Post-Doctoral Scientists and Research Assistants

Post-Doctoral Scientists and Research Assistants– Rush Alzheimer's Disease Center

The Rush University Alzheimer's Disease Center (RADC) is a leading experimental and epidemiological center for studying Alzheimer's disease. Over the past decade, the RADC has carried out numerous community-based cohort studies and generated multi-omic data from human specimens (https://www.radc.rush.edu/). An ongoing effort is to discover and test genetic drivers with multidisciplinary approaches, including single-cell multi-omics, iPSC-based stem cell modeling, and CRISPR gene perturbations. To embark on this exciting and ambitious research endeavor, we seek highly motivated Post-Doctoral Scientists in Molecular Genomics. 

Responsibilities

• Conduct and develop new single-cell omics projects 
• Conduct CRISPR-based genetic screening to manipulate potential disease driver genes
• Develop cellular reporter assays to detect and measure disease phenotypes 
• Run bioinformatics and computational analysis 
• Graph and compile data and write manuscripts for publications 

 Requirements

• Ph.D. or equivalent degree in the fields of molecular biology, stem cell biology, genetics, genomics, bioinformatics, neuroscience, or related fields
• Extensive demonstrated experience in molecular biology and next-generation sequencing
• Experience with single-cell multi-omics 
• Excellent skills and experience in CRISPR-based genetic screening and data analysis
• Experience with high-throughput and high-content screening 
• Proficiency with bioinformatics and computational analysis  
• Demonstrated skills in organization, analysis, and communication 
• Proven ability to work independently and in collaborative team environments