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Senior Scientist, Immunogenicity

Andover, Massachusetts
Closing date
Jan 16, 2022

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Life Sciences, Immunology, Physical Sciences, Chemistry
Position Type
Full Time
Job Type
Senior Scientist
Organization Type
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Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

What You Will Achieve

The Immunogenicity Sciences Group within the BioMedicine Design (BMD) department is seeking a motivated and dynamic Immunogenicity Senior Scientist to work within the team and contribute to immunogenicity risk assessment across a diverse array of therapeutic protein modalities and disease areas.

The role has responsibility for establishing and executing laboratory-based predictive immunogenicity & immunogenicity reduction technologies, in particular in vitro cellular assays. The role will be to work independently, use scientific judgment in making decisions within the area of technical expertise, and propose new options to develop new processes and assays to advance Immunogenicity Sciences knowledge and technology.

In collaboration with Immunogenicity Scientists, Protein engineers and other lines within BMD, the Senior Scientist will provide continuous support to Pfizer biologics portfolio projects.

How You Will Achieve It

  • Isolate and culture various human blood-derived cell types to support the Immunogenicity team and other partner lines in delivering high-value data in support of Pfizer biologics portfolio projects
  • Conduct and analyze results of immunogenicity risk assessment studies
  • Organize and present data to the immunogenicity team to inform decisions
  • Demonstrate innovative thinking to investigate and establish novel techniques or technologies to advance, improve or optimize scientific practices and procedures in the discipline
  • Effectively interacts within Immunogenicity team and across BMD to support projects advancement
  • Provides mentoring to junior members of the team



  • PhD with 1-3 years industry/academia experience in the field of immunology, biotherapeutics or vaccine
  • Solid understanding of perturbations of the immune system in diseases as diverse as cancer and autoimmunity
  • Extensive hands-on experience with human PBMC isolation and storage, human immune cell functional in vitro assays, magnetic beads cell separation, and flow cytometry
  • Ability to work under limited supervision, including data analysis and report
  • Scientific curiosity, initiative, and ability to quickly adapt to changing priorities
  • Excellent interpersonal and skills. The position requires an individual who will thrive in a team
  • Track record of mentoring
  • Ability to excel in a collaborative, fast paced and dynamic environment
  • Excellent oral and written communication skills. Proficiency with personal computers, including word processing, spreadsheets, PowerPoint and relevant scientific software


  • Experience with molecular immunology
  • Track record of method development skills with novel and complex methods
  • Experience in automating assays

  • Sitting, standing, walking, bending, ability to perform complex data analysis

Other Job Details:
  • Last Date to Apply: January 18, 2022
  • Eligible for Employee Referral Bonus
  • Eligible for Relocation Package


Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development

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