Research Scientist, In Vivo Pharmacology

Vision impairment has a broad-ranging adverse influence on patients, their families, and the societies. Glaucoma and age-related macular degeneration (AMD) are the leading causes of severe vision loss in elderly population worldwide. In the Ophthalmology department at Novartis Institutes for BioMedical Research (NIBR), we are committed to developing transformative therapies to save sight and restore vision to improve the lives of patients with glaucoma, AMD, and other blinding diseases.

We are seeking a highly motivated, innovative, and collaborative research scientist to join the in vivo pharmacology team for developing ground-breaking therapies. The individual will work in a collaborative, matrixed team environment, participate in designing and executing experiments in genetic and pharmacological animal models to support drug discovery efforts in ocular disease. In addition, the individual will also play a role in developing animal models and disease-relevant endpoints.

Your responsibilities include, but are not limited to:
•Plan, design and conduct in vivo pharmacology studies
•Perform extensive hands-on in vivo work including animal handling, compound administration, surgical procedures and tissue collection
•Conduct ex vivo protein, gene expression and imaging analyses
•Establish, optimize and characterize mouse or rat model of ocular diseases and develop assays to evaluate the effect of the therapeutics
•Work collaboratively within group, unit and across multi-disciplinary teams of scientists
•Maintain accurate, well-organized experimental records, perform data analysis, organize and communicate the results to team members, and present research progress at lab, unit and departmental meetings

What you will bring to the role:

•Bachelor’s or master’s degree in Biology, Pharmacology, Neuroscience, or similar field
•2+ years of recent and hands-on in vivo experience, including animal restraint, and compound administration via various routes, tissue collection and tissue dissection. Experience with ocular disease models is preferred, but not required.
•Proficiency in standard biological laboratory techniques, including hands-on experience with DNA, RNA extraction, PCR, ELISA, Western blot, immunostaining, and bio-microscopy
•Strong ability and desire to learn surgical skills and new technologies
•Detail-oriented, self-motivated team player, with the ability to work independently
•Good organizational skills and problem-solving skills
•Ability to analyze data with high quality standards and to effectively communicate the experimental results

799 million. That’s how many lives our products touch. And while we’re proud of that fact, in this world of digital and technological transformation, we must also ask ourselves this: how can we continue to improve and extend even more people’s lives?

We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to explore the power of digital and data. Where you’re empowered to risk failure by taking smart risks, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.

We are Novartis. Join us and help us reimagine medicine.

Commitment to Diversity & Inclusion:
Novartis embraces diversity, equal opportunity and inclusion. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration, and empowers our people to unleash their full potential.

Join our Novartis Network: If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.