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Postdoctoral Research Associate

St. Jude Children's Research Hospital
Memphis, Tennessee
Commensurate with experience
Closing date
Feb 20, 2022

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Life Sciences, Cell Biology, Immunology
Position Type
Full Time
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Organization Type
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Job Details


Immunology postdoctoral positions are available in the laboratory of Dr. Hongbo Chi in the Department of Immunology, St. Jude Children’s Research Hospital (, to investigate discovery and cancer immunology, by focusing on cell metabolism of the immune system (immunometabolism) and its implications in cancer and other diseases. As metabolic pathways are inextricably connected to immunity and cancer, understanding these connections allows us to gain new insights into biological concepts and disease targets. We are particularly interested in understanding the metabolic programs (e.g. glucose, lipid, and mitochondrial metabolism), signaling pathways (e.g. mTOR and Hippo kinases; metabolite- and nutrient-induced signaling), and systems-level regulatory networks (e.g. interactions between protein regulators and their targets) in basic T cell and dendritic cell biology and antitumor immunity. To this end, we apply interdisciplinary strategies by integrating immunological and genetic approaches with cutting-edge systems immunology tools, including single-cell transcriptomics, proteomics, metabolomics, network reconstruction, and in vivo CRISPR screening. Please see the following articles published over the past four years for additional information: Nature 600:308 (2021); Nature 595:724 (2021); Nature 591:306 (2021); Cell 184:1245 (2021); Cell Metabolism 32:996 (2020); Nature Reviews Immunology 20:55 (2020); Nature 565:101 (2019); Nature 576:471 (2019); Immunity 51:1012 (2019); Nature 558:141 (2018); Immunity 49:899 (2018); and Science Immunology aas9818 (2018).

St. Jude Children’s Research Hospital, ranked a best children's hospital for pediatric cancer, offers an exceptional research and training environment with state-of-the-art facilities, along with competitive salary and excellent benefits, to postdoctoral fellows.

Minimum Education

Highly motivated individuals with a recent Ph.D. in immunology or cell biology and publication records (minimum of one-first author in a peer-reviewed journal) are encouraged to apply for the open position #44139.  

Contact Information

Hongbo Chi, PhD, Member

Department of Immunology

St. Jude Children’s Research Hospital

262 Danny Thomas Place

Memphis, TN  38105


St. Jude Children's Research Hospital, founded by the late entertainer Danny Thomas, is one of the world's premier centers for the research and treatment of pediatric cancer and other catastrophic childhood diseases. St. Jude is the first and only pediatric cancer center to be designated as a Comprehensive Cancer Center by the National Cancer Institute. Children from all 50 states and from around the world have come through the doors of St. Jude for treatment, and thousands more around the world have benefited from the research conducted at St. Jude - research that is shared freely with the global medical community. St. Jude is the only pediatric cancer research center where families never pay for treatments that are not covered by insurance. No child is denied treatment because of a family's inability to pay.

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