Immunology postdoctoral positions are available in the laboratory of Dr. Hongbo Chi in the Department of Immunology, St. Jude Children’s Research Hospital (www.stjude.org/chi), to investigate discovery and cancer immunology, by focusing on cell metabolism of the immune system (immunometabolism) and its implications in cancer and other diseases. As metabolic pathways are inextricably connected to immunity and cancer, understanding these connections allows us to gain new insights into biological concepts and disease targets. We are particularly interested in understanding the metabolic programs (e.g. glucose, lipid, and mitochondrial metabolism), signaling pathways (e.g. mTOR and Hippo kinases; metabolite- and nutrient-induced signaling), and systems-level regulatory networks (e.g. interactions between protein regulators and their targets) in basic T cell and dendritic cell biology and antitumor immunity. To this end, we apply interdisciplinary strategies by integrating immunological and genetic approaches with cutting-edge systems immunology tools, including single-cell transcriptomics, proteomics, metabolomics, network reconstruction, and in vivo CRISPR screening. Please see the following articles published over the past four years for additional information: Nature 600:308 (2021); Nature 595:724 (2021); Nature 591:306 (2021); Cell 184:1245 (2021); Cell Metabolism 32:996 (2020); Nature Reviews Immunology 20:55 (2020); Nature 565:101 (2019); Nature 576:471 (2019); Immunity 51:1012 (2019); Nature 558:141 (2018); Immunity 49:899 (2018); and Science Immunology aas9818 (2018).
St. Jude Children’s Research Hospital, ranked a best children's hospital for pediatric cancer, offers an exceptional research and training environment with state-of-the-art facilities, along with competitive salary and excellent benefits, to postdoctoral fellows.
Highly motivated individuals with a recent Ph.D. in immunology or cell biology and publication records (minimum of one-first author in a peer-reviewed journal) are encouraged to apply for the open position #44139.
Hongbo Chi, PhD, Member
Department of Immunology
St. Jude Children’s Research Hospital
262 Danny Thomas Place
Memphis, TN 38105