The Center for Cell and Gene Therapy (CAGT) seeks an experienced researcher to assist CAGT Investigators in the development and translation of novel research strategies into the clinic. This includes evaluating the effects of gene modifications on virus-specific T-cells and CAR T-cells that will eventually be used for the treatment of patient with virus-associated diseases and maligancies. The individual will also evaluate blood and biopsy samples from patients on clinical studies to evaluate their in vivo persistence and efficacy.Job Duties
- Cultures gene-modified primary T-cell lines and virus-specific T-cells.
- Evaluates antigen-specific functions of T-cells with immunoassays.
- Analyzes T-cells using TCR sequencing and single cell RNA seq.
- Modifies genes of T-cells to improve their anti-tumor efficacy.
- Performs extensive tissue cultures.
- Performs some experiments with mice.
- Works in an interactive team.
- Attends seminars and presents work in lab meetings.
- Handles patient samples.
- Trains new staff on specific assays.
- Bachelor's degree in a Basic Science or a related field.
- Two years of relevant experience.
- Understanding of immunology, clinical samples or virology.
- Experience in cell culture.
- Must be self-driven and motivated and be able to work independently.
- This position requires attention to detail, good communication skills and a responsible attitude.
- May occasionally have to work on weekends or after hours for patient samples
- Must be flexible as unexpected needs may arise with patients.
- This position requires physical dexterity and reasonable strength.
Baylor College of Medicine requires employees to be fully vaccinated -subject to approved exemptions-against vaccine-preventable diseases including, but not limited to, COVID-19 and influenza.
Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.