CNS Research Associate
We were born of innovation, springing from the curiosity, imagination and dedication of remarkable scientists and healthcare visionaries. Our shared mission is to challenge the inevitability of genetic disease by discovering, developing, and delivering treatments in ways unimaginable – until now.
We don’t follow footsteps. We create the path.
Conduct experiments in the areas of neuroscience, neurodegeneration and cell biology
Use molecular biology, and cell culture techniques (human iPSC-derived neurons, primary neurons, cell lines) to execute studies
Provide technical support in developing and running in-vitro assays for early discovery target assessment.
Provide technical support in running ex-vivo pre-clinical experiments to evaluate treatment efficacy and safety.
Participate in key aspects of general lab management and organization (e.g., managing inventories and stocks of samples, reagents, equipment and materials, and support team members with day to day activities).
Collaborate to perform experiments on the bench in support of the CNS research projects, including new assay development (in-vitro and ex-vivo) and troubleshooting
Data analysis and an extensive literature review
Oversee and/or provide technical support of specialized equipment as needed
Manage CNS research samples and materials
Manage reagents inventories
Education and Experience Requirements
Bachelor’s degree required, Masters in a relevant field preferred (Neuroscience, Molecular Biology, Cell Biology, Gene Therapy).
Minimum of 2years of relevant experience as Lab Assistant or equivalent.
Knowledge of AAV or gene therapy preferred, but not essential.
Adept at conducting routine testing and limited troubleshooting of multiple methods.
Key Skills, Abilities, and Competencies
At least one-year hands on experience performing cell culture and associated techniques (cell line maintenance, DNA/RNA purification, …)
Experience with CNS cell types (neurons, astrocytes) is highly desirable but not required
At least two years hands-on experience in general molecular biology (DNA and RNA isolation, cloning,
sequencing, PCR, RT-PCR, and Q-PCR), protein biochemistry and cell biological approaches.
Able to organize ordering and receiving of lab materials and supplies.
Able to manage samples and perform experiments with some oversight.
Ability to manage competing priorities in a fast-paced environment.
Strong interpersonal skills demonstrated by the ability to lead and gain the assistance and cooperation of others in a team endeavor.
Strong organizational skills and communication skills.
Independently motivated and exceptionally detail oriented.
Ability to learn new techniques and work independently after training
Please be aware that Spark mandates COVID-19 vaccination of all employees regardless of work location. Accommodations may be made in accordance with applicable law.
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Join the Spark Team
We were born of innovation, springing from the curiosity, imagination and dedication of remarkable scientists and healthcare visionaries. Our shared mission is to challenge the inevitability of genetic disease by discovering, developing, and delivering treatments in ways unimaginable - until now.
We don't follow footsteps. We create the path.