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Sarepta Therapeutics
Columbus, Ohio
Closing date
Jan 2, 2022

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Health Sciences, Clinical Research
Position Type
Full Time
Job Type
Organization Type
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Sarepta Therapeutics is seeking a motivated individual with histology and histology related assays. The qualified candidate will provide laboratory support of day-to-day GCLP/GLP testing on muscle/nerve and other tissue types using complex histology methods in accordance with the requirements of approved protocols; maintains records of experiments; assists in analyzing data and prepares laboratory reports. This person may participate in development, GCLP/GLP qualification, and validation of histology related assays to support clinical trials and clinical development decision-making. Primary Responsibilities Include:


  • Performs routine and complex laboratory procedures in histology using frozen section and FFPE techniques.
  • Assist in the execution of GCLP/GLP clinical and non-clinical study sample processing, staining and analysis using a variety of assay formats such as Histochemical special stains, Immunofluorescence and Immunohistochemistry.
  • Collects and analyzes morphometric data in accordance with appropriate statistical procedures, inclusive of graphs, tables, and photographs of the results for image analysis.
  • Assist in sample processing for immunoblotting, and molecular biology studies.
  • Processes tissue, blood, urine, and other samples as needed.
  • Prepare and maintain reagents and chemical inventory.
  • General laboratory maintenance of general and specialized laboratory instrumentation including various types of microscopes and slide scanners.
  • Assists in training new employees on technical procedures as assigned in standard methods, practices, procedures, and equipment operations.
  • Additional duties include completing general lab tasks, preventive maintenance and quality control. Maintaining a clean working area and adheres to proper safety techniques and procedures. Performs miscellaneous related duties as required.
  • Ensure compliance with GCP/GLP guidelines



  • Registered HT (ASCP) or Associate's degree in a chemical, physical or biological science or medical laboratory technology from an accredited institution including clinical laboratory training in an approved MLT program with eligibility to sit for the registry exam.
  • Ability to execute sample handling and analysis with strict adherence to laboratory methods and SOPs.
  • Knowledge of histology techniques (both general and specialized), cryostat-microtomy, microscopy and slide scanners. Experience with muscle and nerve tissue samples preferred.
  • Necropsy skill is highly desired.
  • Demonstrates the ability to communicate clearly across multiple parties, problem solve complex issues, and plan and develop new procedures or policies with initiative to complete all assignments.
  • Desire to work in a high-functioning, collaborative team.
  • Experience with computer productivity software (i.e. Word, Excel, etc.)
  • Image analysis skill is preferred.
  • Excellent written and verbal communication skills
  • Desire to work in a dynamic, fast-paced team environment and to make a difference in the lives of people through our innovative medicines.
  • Recognized by former peers, colleagues, managers and direct reports for attributes congruent with Sarepta Values: Patients First, Action, Unconventional Thinking, Talent, and Integrity.


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