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Research Fellow

Employer
Dana-Farber Cancer Institute
Location
Boston, Massachusetts (US)
Salary
Salary commensurate with experience.
Closing date
Dec 30, 2021

View more

Discipline
Life Sciences, Biomedical Sciences
Position Type
Full Time
Job Type
Postdoc, Postdoc Fellowship
Organization Type
Healthcare/Hospital
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Research Fellow, Insco Laboratory
Dana Farber Cancer Institute
Boston, MA
Full Time

A Post-Doctoral position is available to join the Insco Laboratory in the Department of Medical Oncology at Dana-Farber Cancer Institute. We are looking for an enthusiastic scientist to join our team! This role offers an unusual opportunity to contribute to a new laboratory at the Dana-Farber Cancer Institute in a newly renovated lab space!

RNA biology is exploding and basic discoveries are being rapidly translated to therapies. Given the importance of RNA, RNA quality control is key. Aberrant RNAs require identification and destruction to avoid being translated into abnormal proteins that can contribute to cancer. We found that nuclear RNA surveillance is tumor suppressive in melanoma, the most lethal type of skin cancer. We will utilize the functional in vivo genetics of zebrafish paired with novel molecular techniques to study nuclear RNA surveillance in both zebrafish and human cultured cells. We seek to further the mechanistic understanding of RNA surveillance in cancer and to provide novel therapeutic approaches for melanoma patients.

Requirements:

  • Design, conduct, and troubleshoot experiments involving molecular biology, zebrafish animal models, and cell culture
  • Think independently and creatively while working collaboratively on our team
  • Mentor research technicians
  • Maintain detailed and understandable lab notebooks
  • Interpret and discuss research findings informally and in lab meetings
  • Use existing computational tools to analyze complex data sets, including next generation sequencing data sets, and/or fluently and effectively collaborate with computational biologists to accomplish this.
  • Develop figures to depict research findings, write research and review papers, and present at scientific meetings.

Qualifications:

  • Accomplished and motivated candidates who have attained a PhD or equivalent in the biomedical sciences are encouraged to apply.
  • Candidates with experience in zebrafish modeling, RNA biology, transcriptional biology, and/or cancer biology are encouraged to apply.  
  • Experience generating and analyzing complex datasets (e.g., from ChIPseq, RNAseq, single cell analyses, or CRISPR-Cas9 forward genetic screens) is desirable.
  • Clear thinking, writing, and communication skills are highly valued. 
  • A record of scientific accomplishment as shown by a peer-reviewed original research paper(s) is encouraged.

For more information and to apply, please visit: https://careers.dana-farber.org/research_fellow_insco_lab

About Dana Farber:
Located in Boston, Dana-Farber Cancer Institute (DFCI) is a fantastic place to work. DFCI brings together world-renowned clinicians, innovative researchers, and dedicated professionals to work collaboratively 

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