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Scientist, Microinjectionist (non-PhD)

Employer
Pfizer
Location
Cambridge, Massachusetts
Salary
Competitive
Closing date
Dec 8, 2021

View more

Discipline
Physical Sciences, Chemistry
Position Type
Full Time
Job Type
Staff Scientist
Organization Type
Pharma
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Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

What You Will Achieve

Pfizer's In Vivo Functional Genomics Unit is focused on rapid generation of transgenic mouse models for validation of new drug targets, mechanistic understanding of disease pathology and preclinical testing. The unit applies the latest technical developments in gene editing and transgenic technology to create First-In-Class genetically engineered mouse models (GEMMs).

The position will provide technical support for generation of GEMMs through genome editing in mouse zygotes and will take part in testing and implementation of the latest transgenic technologies.

How You Will Achieve It

  • Support the procedures involved in mouse model generation (embryo production via superovulation, IVF, cryopreservation, electroporation/microinjection, transfer surgery, post-operative care, sampling, genotyping and breeding of animals).
  • Project tracking and colony management.
  • Support the testing of new and experimental technologies for creation of animal models, together with other members of the group.
  • Rigorous compliance with the letter and spirit of all animal welfare and safety protocols.


Qualifications

Must-Have
  • Bachelor's degree in biology or related field with 6 years of experience, or Master's degree with 3 years of experience
  • >2 years of experience with microinjection, implantation surgery and breeding
  • Good understanding of all the scientific and practical steps involved in making transgenic models
  • Ability to engage closely in multiple projects and to track record of timely execution
  • Excellent interpersonal and communication skills; ability to maintain productive and congenial collaborations in a fast-paced environment
  • Devotion to advancing team goals and enthusiasm for contributing to the mission of drug discovery
  • Able to spend significant time at microscope


Nice-to-Have

  • >5 years of experience with microinjection and implantation surgery
  • Experience in cryopreservation and IVF
  • Solid understanding of basic molecular biology techniques used for genotyping


Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development

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