Principle Scientist

Site Name: USA - Pennsylvania - King of Prussia Posted Date: Oct 26 2021 Are you looking for a challenging opportunity that allows you to leverage your technical expertise to work with novel analytical technologies to support the development of pharmaceuticals?  If so, this Principle Scientist role for Biopharmaceutical Analytics and Characterization in Analytical Platforms and Platform Modernization will be an exciting opportunity for you to explore. Product Development and Supply is a highly experienced Chemistry, Manufacturing and Controls (CMC) organization accountable for delivering robust, cost effective and competitive products and manufacturing processes spanning the full life cycle of asset development from Discovery through Commercialization. These activities are delivered through state-of-the-art internal facilities as well as strategic external partners. Collectively, the team is accountable for CMC activities encompassing cell line development, cell culture/ microbial fermentation, purification development, and drug product/ device development. We also pioneer innovative technologies to improve robustness, reduce cost of goods, and improve the patient experience. As a Principle Scientist for Biopharmaceutical Analytics and Characterization in Analytical Platforms and Platform Modernization, you will be a member of a highly skilled team of scientists responsible for the exploration, evaluation, and implementation of state-of-the art analytical technologies to support pharmaceutical process development and manufacturing, with a focus of developing workflows that can accelerate delivery in support of small molecule and biopharmaceutical development. In this dynamic role, you may interact with other labs, internal and external to GSK, to support the training and transfer of analytical methods and technologies. Your primary focus will be in the laboratory to explore, evaluate and implement technologies to expand GSK capabilities in process analytical technologies. A successful person will develop innovative workflows that further capabilities in the analysis of proteins including by participating in development, qualification and transfer of analytical methods that employ such techniques as HPLC, UPLC, LC-MS, LC-MS/MS, CGE, cIEF, and other protein characterization methodologies including instrument control via coding (Python preferred). The role also involves verbal and written communication and requires good organization as well as a broader scientific knowledge.  Both individual and team working are required and therefore the role will suit a scientist with good interpersonal skills, self-motivation and an open mindset to learning new skills in cross-functional teams. Basic Qualifications A Bachelor's degree with at least 10 years of experience in the biotech or pharmaceutical industry. Hands-on experience in analysis of proteins such as HPLC, uHPLC, cIEF, or CGE. An understanding of coding (Python preferred) is desired.  Excellent organization, communication and interpersonal skills are a must.   Preferred Qualifications Master's degree in Pharmaceutics, Biology, Chemistry, Chemical Engineering, or related scientific discipline with 5-7 years of similar experience  OR PhD in Pharmaceutics, Biology, Chemistry, Chemical Engineering, or related scientific discipline with 0-3 years of hands-on experience and knowledge in method development to support characterization and/or product quality of biopharmaceuticals including HPLC, UHPLC, Capillary Electrophoresis, Spectroscopy, LC-MS, LC-MS/MS, etc. An understanding of Process Analytics including automation, informatics, etc. An understanding of the product development life cycle.   *LI-GSK If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. At GSK, the health and safety of our employees are of paramount importance. As a science-led healthcare company on a mission to get ahead of disease together, we believe that supporting vaccination against COVID-19 is the single best thing we can do in the US to ensure the health and safety of our employees, complementary workers, workplaces, customers, consumers, communities, and the patients we serve. GSK has made the decision to require all US employees to be fully vaccinated against COVID-19, where allowed by state or local law and where vaccine supply is readily available. The only exceptions to this requirement are employees who are approved for an accommodation for religious, medical or disability-related reasons. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.