Postdoctoral Fellow, Comparative Medicine

Cambridge, Massachusetts
November 25 2021
Position Type
Full Time
Organization Type

The Global Science and Technology group in Pfizer's Comparative Medicine division is seeking an outstanding postdoctoral researcher to lead project on identifying and validating novel translationally relevant physiological endpoints in preclinical heart failure models. This is an exciting opportunity to work on complex measures of pathophysiology and disease progression in preclinical models of heart failure, and how these measurements can be used as preclinical prognostic biomarkers to aid the evaluation of novel targets against heart failure. The prospective post-doctoral fellow will be responsible in independently designing and performing pioneering experiments under supervision of the mentors. The candidate will present research work internally as well as at external scientific conferences and publish manuscripts in peer-reviewed scientific journals.

We are looking for a candidate with a research background in cardiovascular physiology, cardiac electrophysiology, rare cardiac diseases, heart failure, or cardiac metabolism. This project is ideally suited for a candidate looking to expand their interdisciplinary skills and gain exposure in drug discovery


This post-doctoral fellow will be responsible for developing translational techniques, protocols, and pre-clinical models to understand physiological measures in preclinical models of heart failure. The position involves independent thinking, literature search and execution of experiments under minimal supervision.
  • Develop, refine, and validate preclinical models of heart failure
  • Design and execute pre-clinical experiments to identify and validate translationally relevant prognostic markers in validated models of heart failure
  • Perform in vivo technique such as echocardiography, contrast enhanced ultrasound, exercise tolerance test, calorimetry , cardiovascular telemetry
  • Acquisition and analysis of ECG data from preclinical models of HF
  • Collaborate across the cross functional team to leverage the resources and conduct the studies efficiently.
  • Present the work at various meetings and publish the work in reputed journals in the field.

  • PhD in cardiovascular physiology, cardiovascular pharmacology, cardiac metabolism, or veterinary sciences.
  • 0-3 years of postdoctoral training in academia or industry.
  • Experience in preclinical models of heart failure.
  • Strong collaborative spirit and writing skills evidenced by lead author publications in high impact peer reviewed journals.

  • Experience in ultrasound based imaging, including echocardiography
  • Experience in acquisition and analysis of telemetered ECG data

  • Primarily sitting at adesk and moving through offices.No extra-ordinary requirements.
  • The position will also involve complex data or image analysis which involves advanced software and tools.

Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development


Similar jobs

Similar jobs